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Table 1 Multivariate analysis of overall survival in TCGA

From: Five gene signatures were identified in the prediction of overall survival in resectable pancreatic cancer

Variables   Primary set Validation set  
   Multivariate analysis Multivariate analysis
  HR 95%CI P-value HR 95%CI P-value
Age 1.051 1.006–1.099 0.024 1.003 0.965–1.041 0.871
Surgery method
 Other Method      
 Whipple 2.208 1.414–3.499 0.004 1.182 0.739–1.903 0.491
Radiation
 Yes       
 No 0.329 0.103–1.052 0.043 0.221 0.082–0.604 0.003
Gender
 MALE       
 FEMALE 2.678 0.994–7.211 0.501 0.561 0.267–1.180 0.127
AJCC Stage
 I+ IIA       
 IIB+ III+ IV 1.257 0.397–3.975 0.696 1.756 0.613–5.031 0.295
T Stage
 T1 + T2       
 T3 + T4 1.149 1.042–2.302 0.436 3.348 1.148–9.759 0.026
N Stage
 N0       
 N1 1.469 1.285–4.7444 0.499 1.573 0.076–4.322 0.998
Grade Stage
 G1       
 G2 1.527 0.085–2.824 0.177 1.312 0.682–2.527 0.416
 G3 + G4 2.297 1.217–4.355 0.610 2.510 1.279–4.928 0.707
Risk score 1.100 1.062–1.139 < 0.001 1.068 1.045–1.129 < 0.001