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Table 1 Multivariate analysis of overall survival in TCGA

From: Five gene signatures were identified in the prediction of overall survival in resectable pancreatic cancer

Variables

 

Primary set

Validation set

 
  

Multivariate analysis

Multivariate analysis

 

HR

95%CI

P-value

HR

95%CI

P-value

Age

1.051

1.006–1.099

0.024

1.003

0.965–1.041

0.871

Surgery method

 Other Method

     

 Whipple

2.208

1.414–3.499

0.004

1.182

0.739–1.903

0.491

Radiation

 Yes

      

 No

0.329

0.103–1.052

0.043

0.221

0.082–0.604

0.003

Gender

 MALE

      

 FEMALE

2.678

0.994–7.211

0.501

0.561

0.267–1.180

0.127

AJCC Stage

 I+ IIA

      

 IIB+ III+ IV

1.257

0.397–3.975

0.696

1.756

0.613–5.031

0.295

T Stage

 T1 + T2

      

 T3 + T4

1.149

1.042–2.302

0.436

3.348

1.148–9.759

0.026

N Stage

 N0

      

 N1

1.469

1.285–4.7444

0.499

1.573

0.076–4.322

0.998

Grade Stage

 G1

      

 G2

1.527

0.085–2.824

0.177

1.312

0.682–2.527

0.416

 G3 + G4

2.297

1.217–4.355

0.610

2.510

1.279–4.928

0.707

Risk score

1.100

1.062–1.139

< 0.001

1.068

1.045–1.129

< 0.001