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Table 5 Factors influencing morbidity and mortality on bivariate logistic regression of patients with perforated Peptic ulcer disease in four teaching hospital in Addis Ababa, Ethiopia

From: Pattern and outcome of perforated peptic ulcer disease patient in four teaching hospitals in Addis Ababa, Ethiopia: a prospective cohort multicenter study

Variable Complications N (%)
N = 16
No Complications N (%)
N = 68
P-valueDeath N (%)
N = 3
Discharged improved N (%)
N = 94
P-value
SexMale16 (19.04)68 (80.1) 3(3.6)81(96.4) 
 Female0 (0)13(100)0.1360130.787
Age11–203 (17.6)14 (82.4) 0 (0)17(100) 
 21–304(9.8)37 (90.2) 0(0)41(100) 
 31–404 (17.4)19 (82.6) 2 (8.7)21(91.3) 
 41–501 (25)3 (75) 0(0)4 (100) 
 51–601 (16.7)5 (83.3) 0 (0)6(100) 
 61–702 (50)2 (50) 1(25)3(75) 
 71–801 (50)1 (50)0.080(0)2 (100)0.003
AddressAA12 (14.6)70(85.4) 3 (3.6)79(96.4) 
 Outside4 (26.7)11(73.3)0.3910 (0)15(100)0.475
ReligionOrthodox11(14.9)63(85.1) 2 (2.7)73 (98.3) 
 Muslim4(25)12(75) 1 (6.3)15 (93.7) 
 Others Christians0(0)6(100)0.3100 (0)6 (100)0.746
History of PUDHistory of PUD13 (17.8)60 (82.2) 3 (4.1)70 (95.90 
 No history of PUD3 (12.5021(87.50 0 (0)24(100)0.337
SmokingYes5 (15.6)27(84.40) 0 (0)32(100) 
 No11(16.9)54 (84.100.9223 (4.6)62 (95.4)0.240
AlcoholYes4 (16.4)38(83.6) 0 (0)44 (100) 
 No10 (18.70)43 (81.3)0.212  0.126
Khat use/Catha edulisYes2 (12.5)14 (87.5) 1(5.9)16 (94.1) 
 NO15 (18.5)66 (81.5)0.1412 (2.5)78 (97.5)0.323
Co-morbidityYes0 (0)3 (100) 1(33.3)2 (66.70 
  16 (17)78(83)   0.00
NSAID useyes1 (50)1(50) 0 (0)2 (100) 
 No15 (15.8)80 (84.2)0.0763 (3.2)92(96.8)0.809
Hx of PUDYes13(17.8)60 (82.2) 3 (4.1)70 (95.9) 
 No3 (12.5)21(87.5)0.13900 
H.Pylri infectionPresent1 (33.3)2 (66.7)0.6471 (33.3)2 (66.700.02
Duration at presentation<  24 h.4 (9)40 (91) 0(0)44 (100) 
 24–48 h.5 (15.1)28 (84.9) 1 (3)32 (97) 
 48–72 h.3 (27.3)7(72.7) 0(0)10 (100) 
 > 72 h.4 (40)6 (60)0.0042 (20)8 (80)0.003
WBC countRaised7 (15.6)38 (84.4) 0 (0)45 (100) 
 Normal9 (17.3)43 (82.7)0.6103 (5.8)49 (94.2) 
CXR findingFree air14 (16.7)69 (83.3) 2 (2.4)81(97.6) 
 Not detected1(9.1)10 (90.9) 0 (0)11(100) 
 Not done1 (33.3)2 (66.7) 1 (33.3)2 (66.7) 
HypotensionYes9 (52.9)8 (47.1)0.0003 (17.6)14 (82.4)0.001
Perforation size< 10 mm7 (9.2)69 (90.8) 0 (0)79 (100) 
 10-20 mm5 (41.7)7 (59.3) 1 (8.3)11(91.7) 
 > 20 mm1 (50)1 (50) 2 (100)0 (0)0.000
 Sealed0 (0)4 (100)0,0460 (0)1(100) 
contamination<  1 Lts7 (9.7)65 (90.3) 1 (1.4)71 (98.6) 
 1–3 Lts7 (33.3)14 (66.7) 1 (4.8)20 (95.2) 
 > 3 Lts1 (33.3)2 (66.7)0.0001 (25)3 (75)0.006
Procedure doneSimple closure0 (0)0 (0) 0 (0)0 (0) 
 Pedicled omental11(16.9)54 (83.1) 3 (4.6)62(95.4) 
 Free omental5 (18.5)23 (81.5)0.3990 (0)27 (100) 
Drainage left 15 (16.8)74 (83.2) 3 (3.4)86 (96.6)