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Table 3 Clinicopathologic characteristics of included studies (continued)

From: Surgical treatment to multiple primary lung cancer patients: a systematic review and meta-analysis

Study (Year)Perioperative MorbidityPerioperative MortalityResectionAdjuvant TherapyMedian Survival
(months)
5-year OS
SublobarStandardTotalSublobarStandardTotalSublobarStandard
Van Rens (2000) [11]NA12 (14.1%)3241NA55.2NANA19%NANA
Doddoli (2001) [12]4 (11%)5 (13%)122611 (29%)31NANA32%NANA
Trousse (2007) [13]34 (27.2%)6 (29.0%)438262 (49.6%)34.932NANA34%NANA
De Leyn (2008) [14]16 (44.4%)1 (2.8%)26106 (16.7%)49.4NANA38.1%NANA
Riquet (2008) [15]66 (28.2%)20 (8.6%)5418062 (26.5%)30NANA32.7%36.4%34.1%
Lee (2009) [16]NANA3523NANANANA66%59%75%
Voltolini (2010) [17]16 (37%)3 (7%)281518 (42%)32343234%29%42%
Hamaji (2013) [18]47 (29.2%)01233814 (8.7%)72.9NANA60.8%NANA
Ishikawa (2014) [19]NA054396 (6.5%)NANANA87.0%NA92.5%
Xiao (2017) [20]3 (5.8%)0381421 (40.4%)52603840.6%NANA
  1. Notes: NA Not available, OS Overall survival