Table 2 Histopathological factors and their distribution within different age groups
From: Resection of intrahepatic cholangiocarcinoma in elderly patients – is it reasonable?
<70 n = 99 | > 70 n = 51 | p-value | Young < 50 n = 23 | Middle-age 50–70 n = 76 | Old > 70 n = 51 | p-value | ||
|---|---|---|---|---|---|---|---|---|
Tumor sizea (cm) | Mean Median (IQR) | 7.76 7 (4.6–10.5) | 7.38 6.75 (5–9) | 8.45 7.5 (6.2–11) | 7.55 6.5 (4.5–10) | 7.38 6.75 (5–9) | ||
≤ 10 / > 10 cm | 69 / 28 | 40 / 10 | 0.245 | 15 / 8 | 54 / 20 | 40 / 10 | 0.386 | |
≤ 5 / > 5 cm | 26 / 71 | 12 / 38 | 0.713 | 4 / 19 | 22 / 52 | 12 / 38 | 0.466 | |
Multifocality | yes / no | 35 / 64 | 11 / 40 | 0.083 | 12 / 11 | 52 / 24 | 40 / 11 | 0.074 |
Number of nodulesb | Mean | 2.1 | 1.56 | 2.86 | 1.86 | 1.56 | ||
≤3 / ≥4 | 79 / 16 | 45 / 4 | 0.154 | 16 / 6 | 63 / 10 | 45 / 4 | 0.098 | |
T-stage | T1 + T2 / T3 + T4 | 72 / 27 | 40 / 11 | 0.447 | 14 / 9 | 58 / 18 | 40 / 11 | 0.246 |
N-stagec | N0 / N1 | 53 / 35 | 37 / 8 | 0.010 | 13 / 9 | 40 / 26 | 37 / 8 | 0.037 |
R-stage | R0 / R1 | 86 / 13 | 45 / 6 | 0.812 | 20 / 3 | 66 / 10 | 45 / 6 | 0.972 |
Grading | G1 + G2 / G3 + G4 | 59 / 32 | 36 / 12 | 0.221 | 14 / 8 | 45 / 24 | 36 / 12 | 0.468 |