Table 3 Combination of hazard ratio (HR) associated with recurrence-free survival of duodenal gastrointestinal stromal tumors
|  | No. of studies | No. of patients | HR | 95%CI | p value | Heterogeneity (I2), % | Egger’s test (p value) |
|---|---|---|---|---|---|---|---|
Gender (Male vs. Female) | 8 | 500 | 1.42 | 1.02–1.97 | 0.04 | 0 | – |
Age (≥60 vs. < 60) | 5 | 343 | 1.12 | 0.72–1.77 | 0.61 | 0 | – |
Tumor size (≥5 vs. < 5 cm) | 8 | 550 | 3.59 | 2.32–5.55 | < 0.001 | 26 | – |
No. of mitosis/50 HPF (≥5 vs. < 5) | 8 | 550 | 4.10 | 2.11–7.98 | < 0.001 | 62 | – |
Type of surgery (PD vs. LR) | 10 | 623 | 1.93 | 1.39–2.69 | < 0.001 | 0 | 0.639 |
Imatinib treatment (Yes vs. no) | 7 | 525 | 0.95 | 0.60–1.49 | 0.82 | 0 | – |
Risk grade (High/Other) | 3 | 135 | 6.33 | 2.04–19.66 | 0.001 | 33 | – |