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Fig. 1 | BMC Surgery

Fig. 1

From: Retrospective analysis of seven cases of pancreatic mixed adenoneuroendocrine carcinoma from a high-volume center and review of the literature

Fig. 1

Imageological and pathological characteristics of pMANECs. Patient No. 24 (A1) A huge tumor located at the distal pancreas (red arrow) is heterogeneously enhanced in the arterial phase. The tumor caused a mass effect and presented a close relationship to the left kidney (blue arrow) and splenic flexure of the colon (yellow arrow). Neuroendocrine tumors were suspected preoperatively in this case. (A2) The coronal reconstruction showed that the tumor was fed mainly by branches of the splenic artery and inferior mesentery artery (red arrow). (B1) The primary lesion was composed of a poorly differentiated NEC component (left, small cell NEC) and a moderately differentiated adenocarcinoma component (right) (HE, 40×). (B2) The NEC component consists of diffuse tumor cells with prominent mitosis (HE, 200×). (C1) The adenocarcinoma component was composed of infiltrating duct-like structures and irregular neoplastic glands with intensive desmoplastic stromal reaction (HE, 200×). The typical neuroendocrine marker synaptophysin (C2). HE, hematoxylin and eosin staining; IHC, immunohistochemical staining

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BMC Surgery

ISSN: 1471-2482

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