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Table 2 Studied population related to hypocalcemia

From: Postoperative hypocalcemia: analysis of factors influencing early hypocalcemia development following thyroid surgery

Variable

Hypocalcemia

(n = 795)

Normocalcemia

(n = 1313)

P value

Sex

 female

701 (42%)

968 (58%)

P < 0.0001

 male

94 (21.4%)

345 (78,6%)

 

Age (y)

 mean ± sd

55.03 (±13,87)

54.01 (±13.47)

N.S.

 range

   

Age groups

  < 40

114 (36.9%)

195 (63.1%)

 

 40–50[

190 (43.3%)

249 (56.7%)

 

 50–60[

211 (38.6%)

336 (61.4%)

N.S.

  > 60

280 (34.5%)

532 (65.5%)

 

Post-menopausal age (tot.1669)

 yes

40.1%

59.9%

N.S.

 no

45.2%

54.8%

 

Preoperative diagnosis

 malignant

301 (36.5%)

523 (63.5%)

N.S.

 benign

494 (38.5%)

790 (61.5%)

 

Hyperthyroidism

 yes

148 (38.8%)

234 (61.2%)

N.S.

 no

647 (37.5%)

1115 (62.5%)

 

Thyroiditis

 yes

272 (37.4%)

455 (62.6%)

N.S.

 no

523 (37.9%)

858 (62.1%)

 

Diabetes

 yes

63 (34.8%)

118 (65.2%)

N.S.

 no

732 (38%)

1195 (62%)

 

Hypertension

 yes

181 (31.3%)

420 (68.7%)

P < 0.001

 no

607 (40.3%)

900 (59.7%)

 

Definitive histological diagnosis (tot. 1914)

 malignant

270 (40.5%)

397 (59.5%)

N.S.

 benign

458 (36.7%)

789 (63.7%)

 

Surgical procedure

 total thyroidectomy

782 (38.8%)

1232 (61.2%)

P < 0.001

 lobectomy

13 (13.8%)

81 (86.2%)

 

Total number of parathyroid glands identified during operation (tot. 1202)

 0

2 (12.5%)

  

 1

14 (20.6%)

 

N.S.

 2

125 (32.1%)

  

 3

221 (33.7%)

  

 4

28 (38.4%)

  

Preoperative calcium levels (mg/dl)

 mean ± sd

9.172 (±0.38)

9.35 (±0.43)

N.S.

Preoperative pth (pg/ml)

 mean ± sd (tot. 813)

59.03 (±24.336)

56.78 (±21.195)

N.S.

Calcium drop from preoperative to postoperative (24 h)

 mean ± sd

1.67 (±0.49)

0.920 (±0.47)

P < 0.001