Table 1 Pre-operative and intra-operative patients’ characteristics in 46 IBD patients treated with anti-TNFα compared to anti-TNFα naive
Patients’ characteristics | Anti-TNFα treat. 18/46 (39.1%) | Anti-TNFα naïve 28/46 (60.9%) | Uni-variate |
|---|---|---|---|
Age (mean ± SD) | 38.7 ± 16.36 | 44.39 ± 12.62 | ns |
Female | 11/18 (61.1%) | 14/28 (50%) | ns |
Body mass index | 24.93 (±SD 6.12) | 24.7 (±SD 5.37) | ns |
Type of disease n (%) | ns | ||
Crohn’s disease | 13/18 (72.2%) | 19/28 (67.9%) | |
Ulcerative colitis | 5/18 (27.8%) | 9/28 (32.1%) | |
Smoking n (%) | ns | ||
Non-or ex-smoker | 14/18 (77.8%) | 22/28 (78.6%) | |
Smoker | 4/18 (22.2%) | 6/28 (21.4%) | |
Steroids n (%): | 7/18 (38.9%) | 9/28 (32.1%) | ns |
Immuno-modulators n (%): | 8/18 (44.4%) | 7/28 (25%) | |
NSAID intake preoperative n (%): | 0 | 1/28 (3.6%) | ns |
Anti-Coagulant intake n (%): | 1/18 (5.6%) | 0 | ns |
Harvey-Bradshaw Index in CD patient more than median (7.5) n (%): | 4/18 (36.4%) | 8/28 (61.5%) | ns |
Pre-operative Albumin mmol/l (mean ± SD) | 33.22 ± 7.53 | 36.89 ± 4.36 | ns |
Pre-operative Haemoglobin mmol/l (mean ± SD) | 7.86 ± 0.94 | 8.09 ± 1.01 | ns |
Nutritional risk screening score n (%) | ns | ||
No risk | 6/18 (33.3%) | 20/28 (71.4%) | |
Mild | 6/18 (33.3%) | 4/28 (14.3%) | |
Moderate | 3/18 (16.75) | 2/28 (7.1%) | |
Sever | 3/18 (16.7%) | 2/28 (7.1%) | |
Pre-operative parenteral nutrition n (%): | 5/18 (27.8%) | 1/28 (3.6%) | p = 0.028 |
Steroid stress dose n (%): | 5/18 (27.8%) | 0 | p = 0.003 |
Dexamethasone n (%) | ns | ||
4 mg | 1/18 (5.6%) | 1/28 (3.6%) | |
8 mg | 2/18 (11.1) | 9/28 (32.1%) | |
Pre-operative Epidural analgesia n (%): | 5/18 (27.8%) | 7/28 (25%) | ns |
Access to abdomen n (%) | ns | ||
Laparoscopic | 13/18 (72.2%) | 17/28 (60.7%) | |
Converted | 3/18 (16.7%) | 2/28 (7.1%) | |
Open | 2/18 (11.1%) | 9/28 (32.15%) | |
Type or resection n (%) | ns | ||
SM & IC | 9/18 (50%) | 11/28 (39.3%) | |
Colectomy and/or Rectal | 8/18 (44.4%) | 12/28 (42.9%) | |
Stoma closure | 1/18 (5.5%) | 5/28 (17.8%) | |
Post-operative Epidural analgesia n (%): | 6/18 (33.3%) | 12/28 (42.9%) | ns |
Post-operative NSAID used n (%): | 0 | 2/28 (7.1%) | ns |
Post-operative parenteral nutritional support n (%): | 5/18 (27.8%) | 1/28 (3.6%) | p = 0.028 |