Impact of postoperative complications on long-term survival following surgery for T4 colorectal cancer

BMC Surgery

Table 4 Uni- and multivariate analyses of risk factors for overall and recurrence-free survival in the entire cohort (n = 106)

Variable	Univariate P value	Multivariate P value	Hazard Ratio (95% Confidence Interval)
Age ≥ 60 (years)	0.76
Male sex	0.37
BMI ≥ 30 (kg/m²)	0.79
ASA score ≥ 2	0.12
Elevated CEA	0.03	0.46
Colon vs rectum	0.59
Synchronous metastases	0.03	0.21
Neoadjuvant treatment	0.45
Emergent surgery	0.46
Laparoscopic approach	0.51
Multiple organ resection	0.88
Synchronous liver resection	0.43
N+ status	0.009	0.01	3 (1–7)
R1 margins	0.03	0.08
Postoperative complications	0.37
Grade III-IV complications	0.57
Adjuvant chemotherapy	0.80

Footnotes: BMI indicates body mass index, ASA American Society of Anesthesiologists, CEA carcinoembryonic antigen

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