Table 2 Preoperative and postoperative AICS values and ranks according to clinicopathological features
From: Perioperative dynamics and significance of plasma-free amino acid profiles in colorectal cancer
AICS value | p-value | Decrease in post-op AICS value, N (%) | Decrease in post-op AICS rank, N (%) | ||
|---|---|---|---|---|---|
Pre-op | Post-op | ||||
Pre-op AICS rank B + C | |||||
TNM stage | |||||
0 (N = 1) | 9.1 | 6.7 | NA | 1 (100) | 1 (100) |
I (N = 17) | 7.7 ± 1.4 | 3.4 ± 2.4 | < 0.001 | 17 (100) | 15 (88) |
II (N = 21) | 8.2 ± 1.3 | 5.0 ± 3.5 | < 0.001 | 18 (86) | 15 (71) |
III (N = 23) | 8.0 ± 1.7 | 3.3 ± 3.6 | < 0.001 | 21 (91) | 18 (78) |
Tumor location | |||||
right (N = 17) | 8.0 ± 1.6 | 2.3 ± 2.5 | < 0.001 | 17 (100) | 17 (100) |
left (N = 39) | 8.2 ± 1.4 | 4.7 ± 3.4 | < 0.001 | 34 (87) | 28 (72) |
unknown (N = 6) | 7.1 ± 1.5 | 2.2 ± 3.7 | 0.031 | 6 (100) | 4 (67) |
Differentiation status | |||||
well (N = 15) | 8.1 ± 1.5 | 4.3 ± 3.0 | < 0.001 | 14 (93) | 13 (87) |
moderate (N = 34) | 8.1 ± 1.5 | 3.8 ± 3.6 | < 0.001 | 30 (88) | 25 (74) |
poor (N = 3) | 8.0 ± 1.6 | 3.4 ± 2.9 | 0.25 | 3 (100) | 3 (100) |
other (N = 10) | 7.8 ± 1.7 | 4.0 ± 2.9 | 0.002 | 10 (100) | 8 (80) |
Histological type | |||||
tubular AC (N = 43) | 8.1 ± 1.4 | 3.7 ± 3.3 | < 0.001 | 39 (91) | 36 (84) |
papillary AC (N = 5) | 7.6 ± 1.7 | 5.3 ± 3.0 | 0.063 | 5 (100) | 3 (60) |
poorly diff. AC (N = 6) | 7.5 ± 1.2 | 4.3 ± 2.9 | 0.063 | 5 (83) | 4 (67) |
mucinous AC (N = 3) | 9.6 ± 0.1 | 7.2 ± 1.8 | 0.25 | 3 (100) | 2 (67) |
other (N = 5) | 7.1 ± 1.6 | 2.3 ± 4.1 | 0.063 | 5 (100) | 4 (80) |
Treatment method | |||||
resection (N = 42) | 8.1 ± 1.3 | 4.3 ± 3.1 | < 0.001 | 38 (90) | 33 (79) |
resection + adj CT (N = 20) | 8.0 ± 1.8 | 3.2 ± 3.6 | < 0.001 | 19 (95) | 16 (80) |
Pre-op AICS rank C | |||||
TNM stage | |||||
0 (N = 1) | 9.1 | 6.7 | NA | 1 (100) | 1 (100) |
I (N = 8) | 9.0 ± 0.5 | 3.6 ± 2.5 | 0.008 | 8 (100) | 8 (100) |
II (N = 16) | 8.8 ± 0.5 | 5.7 ± 3.1 | 0.001 | 14 (88) | 11 (69) |
III (N = 12) | 9.5 ± 0.3 | 4.7 ± 3.6 | < 0.001 | 12 (100) | 9 (75) |
Tumor location | |||||
right (N = 10) | 9.1 ± 0.5 | 3.0 ± 2.9 | 0.002 | 10 (100) | 10 (100) |
left (N = 26) | 9.0 ± 0.6 | 5.6 ± 3.0 | < 0.001 | 24 (92) | 18 (69) |
unknown (N = 1) | 9.6 | 7.7 | NA | 1 (100) | 1 (100) |
Differentiation status | |||||
well (N = 10) | 9.0 ± 0.5 | 4.9 ± 2.9 | 0.002 | 10 (100) | 9 (90) |
moderate (N = 21) | 9.0 ± 0.6 | 4.6 ± 3.6 | < 0.001 | 19 (90) | 15 (71) |
poor (N = 2) | 8.9 ± 0.3 | 5.1 ± 0.8 | NA | 2 (100) | 2 (100) |
other (N = 4) | 9.6 ± 0.3 | 6.5 ± 2.1 | 0.125 | 4 (100) | 3 (75) |
Histological subtype | |||||
tubular AC (N = 28) | 9.0 ± 0.5 | 4.3 ± 3.2 | < 0.001 | 26 (93) | 24 (86) |
papillary AC (N = 3) | 8.7 ± 0.5 | 7.0 ± 2.5 | 0.25 | 3 (100) | 1 (33) |
poorly diff. AC (N = 2) | 8.9 ± 0.3 | 5.1 ± 0.8 | NA | 2 (100) | 2 (100) |
mucinous AC (N = 3) | 9.6 ± 0.1 | 7.2 ± 1.8 | 0.25 | 3 (100) | 2 (67) |
other (N = 1) | 9.7 | 9.6 | NA | 1 (100) | 0 |
Treatment method | |||||
resection (N = 27) | 8.9 ± 0.5 | 4.9 ± 3.1 | < 0.001 | 25 (93) | 22 (81) |
resection + adj CT (N = 10) | 9.6 ± 0.3 | 5.3 ± 3.6 | 0.002 | 10 (100) | 7 (70) |