A prediction study of warfarin individual stable dose after mechanical heart valve replacement: adaptive neural-fuzzy inference system prediction

Table 3 The ideal predicted percentage of warfarin in patients in the validation groups

Models	MAE(95%CI)	Under predicted percentage n (%)	Ideal predicted percentage n (%)	Over predicted percentage n (%)	MSE(95%CI)
ANFIS_iv	0.581(0.559~0.602)	472 (15.7)	1911 (63.7)	617 (20.6)	0.688 (0.637~0.738)
ANFIS_stra-iv	0.621 (0.600~0.643)	632 (21.1)	1786 (59.5)	582 (19.4)	0.743 (0.688~0.798)
ANFIS_ev	0.603 (0.573~0.633)	160 (9.8)	993 (60.6)	486 (29.7)	0.739 (0.668~0.809)
ANFIS_stra-ev	0.621 (0.592~0.650)	273 (16.7)	934 (57.0)	432 (26.4)	0.738 (0.665~0.810)

The subscript “stra” in the model symbols stratified training group, “iv” symbols internal validation group and “ev” symbols external validation group. MSE: mean squared error; MSE: mean absolute error (MAE); the ideal predicted percentage was defined as the percentage of patients whose predicted warfarin dose was within 20% of the actual dose

ISSN: 1471-2482