Control group (n = 11) | Humigard group (n = 11) | P value | |
---|---|---|---|
Baseline Characteristics | |||
Male gender | 8 (72%) | 7 (63%) | 0.72 |
Age (years) | 47.3 ± 13.0 | 48.0 ± 11.0 | 0.88 |
Weight (kg) | 83.8 ± 24.1 | 76.5 ± 15.3 | 0.40 |
Body mass index (kg/m2) | 27.8 ± 7.2 | 27 ± 4.3 | 0.61 |
Indications for transplantation | |||
Hepatitis C | 3 | 2 | |
Non-alcoholic steato-hepatitis | 1 | 1 | |
Autoimmune hepatitis | 0 | 3 | |
Primary sclerosing cholangitis | 2 | 0 | |
Primary biliary cirrhosis | 1 | 1 | |
Hepatocellular cancer | 1 | 3 | |
Alcoholic cirrhosis | 1 | 0 | |
Other | 2 | 1 | |
Prognostic Values | |||
MELD | 19.2 ± 6.4 | 20.6 ± 8.6 | 0.66 |
SOFA | 10.1 ± 2.6 | 11.1 ± 2.2 | 0.34 |
Apache II | 19.9 ± 4.5 | 18.4 ± 5.5 | 0.53 |
Intraoperative Factors | |||
Acetate-buffered crystalloid (ml) | 3454.6 ± 2841 | 3681.8 ± 2003 | 0.39 |
Albumex (20%) (ml) | 436.4 ± 478 | 490.9 ± 561 | 0.80 |
Platelets (pooled adult units) | 0 (0:2) | 0 (0:1) | 0.85 |
FFP (units) | 2 (0:4) | 1 (0:3) | 0.67 |
Cryoprecipitate (units) | 0 (0:8) | 0 (0:9) | 0.43 |
Red Blood cells (units) | 0 (0:3) | 2 (0:3) | 0.43 |
Donor blood administered (ml) | 287.3 ± 149.5 | 750 ± 240 | 0.12 |
Cell saved blood returned (ml) | 2319.8 ± 2377 | 2731.5 ± 3221 | 0.74 |
Duration of surgery (hours) | 9.7 ± 1.5 | 9.3 ± 2.3 | 0.63 |