Prognostic value of preoperative inflammatory response biomarkers in patients with esophageal cancer who undergo a curative thoracoscopic esophagectomy

Table 6 Univariate and multivariate analysis of prognostic factors in 46 elderly patients with esophageal cancer

Variables	Patients (n = 46)	Category or characteristics	Univariate			Multivariate
Variables	Patients (n = 46)	Category or characteristics	HR	95 % CI	p value	HR	95 % CI	p value
Gender	5/41	(female/male)	3.114	0.611–56.892	0.201
pStage	31/15	(1,2/3)	5.22	1.824–16.080	0.0023	5.22	1.824–16.080	0.0023
Tumor size	11/35	(3</≥3)	0.976	0.333–3.529	0.9666
Operation time	32/14	(600</≥600)	1.761	0.615–4.929	0.2822
Intraoperative blood loss	23/23	(500</≥500)	0.981	0.349–2.820	0.9707
LMR	25/21	(≥4/4<)	1.118	0.368–3.175	0.837
NLR	12/34	(≥1.6/1.6<)	0.853	0.464–1.535	0.718
PLR	25/21	(147</≥147)	1.3	0.464–3.712	0.616
SCC antigen	33/13	(1.5</≥1.5)	2.261	0.689–6.565	0.167

LMR lymphocyte to monocyte ratio, NLR neutrophil to lymphocyte ratio, PLR platelet lymphocyte ratio, SCC squamous cell carcinoma, HR hazard ratio, CI, confidence interval

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