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Table 3 Univariate analysis and logistic regression analysis correlations between the number of harvested lymph nodes (12 LNs examined in the high-harvest group or < 12 LNs examined in the low-harvest group) and other variables among 370 stage I-III rectal cancer patients

From: Factors affecting number of lymph nodes harvested and the impact of examining a minimum of 12 lymph nodes in stage I-III colorectal cancer patients: a retrospective single institution cohort study of 1167 consecutive patients

  Low-harvest group High-harvest group Univariate analysis Logistic regression analysis
Variables (n = 163) (%) (n = 207) (%) P-value ORa (95 % CIb) P-value
Gender     
 Male/Female 103 (63.2)/60 (36.8) 134 (64.7)/73 (35.3) 0.759 - -
Age (y/o)     
65/<65 120 (60.9)/77 (39.1) 295 (49.2)/305 (50.8) 0.285 - -
Tumor size (cm)     
  < 5/5 129 (79.1)/34 (20.9) 137 (66.2)/70 (33.8) 0.006 1.855 (1.127–3.053) 0.015
Depth of invasion     
 T1 + T2/T3 + T4 81 (41.2)/116 (58.8) 134 (22.4)/466 (77.6) 0.189 0.945 (0.588–1.521) 0.817
TNM stage     
 I + II/III 114 (69.9)/49 (30.1) 121 (58.4)/86 (41.6) 0.023 1.499 (0.925–2.431) 0.101
Tumor histology     
 M + S/Ac 8 (4.9)/155 (95.1) 10 (4.8)/197 (95.2) 0.973 - -
Tumor grade     
 WD + MD/PDd 153 (93.8)/10 (6.2) 193 (93.2)/14 (6.8) 0.808 - -
Vascular invasion     
 Yes/No 31 (19.1)/132 (80.9) 53 (25.6)/154 (74.4) 0.133 1.210 (0.702–2.087) 0.492
Perineural invasion     
 Yes/No 45 (27.7)/118 (72.3) 63 (3054)/144 (69.5) 0.553 - -
Type of surgery     
 Laparoscopic/Open 28 (17.2)/135 (82.8) 33 (15.9)/174 (84.1) 0.750 - -
Preoperative CEAe (ng/ml)     
5/<5 54 (33.2)/109 (66.8) 72 (34.8)/135 (65.2) 0.739 - -
  1. a OR odds ratio
  2. b 95 % CI 95 % confidence interval
  3. c M mucinous carcinoma, S signet-ring cell carcinoma, A adenocarcinoma
  4. d PD poorly differentiated, MD moderately differentiated, WD well differentiated
  5. e CEA carcinoembryonic antigen