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Table 4 Results of monitoring markers

From: 28 day post-operative persisted hypercoagulability after surgery for benign diseases: a prospective cohort study

  Cholecystectomy Hernia surgery
   Median (IQR) p-value Median (IQR) p-value
Fbg (g/l) Fbg* 3.56 (3.17–3.90)   3.45 (3.05–3.95)  
  Fbg 4.16 (3.66–4.66) p*† < 0.001 4.37 (3.71–5.09) p*† < 0.001
  Fbg 3.63 (3.25–4.01) p*‡ = 0.002 3.58 (3.20–4.22) p*‡ < 0.001
D-dimer (μg/l) D-dimer* 96.50 (57.00–139.25)   104.00 (62.00–161.00)  
  D-dimer 409.00 (273.50–577.00) p*† < 0.001 318.50 (173.75–554.25) p*† < 0.001
  D-dimer 109.50 (67.00–155.50) p*‡ = 0.138 123.00 (71.50–216.00) p*‡ < 0.001
PLT (109/l) PLT* 230.00 (200.50–259.50)   212.00 (181.50–248.00)  
  PLT 267.00 (234.50–303.50) p*† < 0.001 262.00 (225.00–312.00) p*† < 0.001
  PLT 227.00 (206.00–275.00) p*‡ = 0.042 216.00 (183.25–267.00) p*‡ = 0.088
F1 + F2 (nmol/l) F1 + 2* 0.17 (0.14–0.21)   0.18 (0.14–0.24)  
  F1 + 2 0.24 (0.19–0.30) p*† < 0.001 0.26 (0.19–0.30) p*† < 0.001
  F1 + 2 0.21 (0.18–0.25) p*‡ = 0.002 0.23 (0.19–0.31) p*‡ < 0.001
Trf (g/l) Trf* 2.33 (2.08–2.65)   2.29 (2.00–2.55)  
  Trf 2.42 (2.28–2.72) p*† = 0.057 2.36 (2.10–2.74) p*† = 0.074
  Trf 2.09 (1.89–2.42) p*‡ = 0.007 2.09 (1.96–2.35) p*‡ = 0.001
Orso (g/l) Oroso* 0.71 (0.62–0.81)   0.73 (0.60–0.88)  
  Oroso 0.95 (0.82–1.07) p*† < 0.001 1.07 (0.85–1.18) p*† < 0.001
  Oroso 0.69 (0.63–0.85) p*‡ = 0.201 0.73 (0.57–0.86) p*‡ = 0.527
CRP (mg/l) CRP* 0.90 (0.45–2.10)   1.10 (0.44–2.60)  
  CRP 3.47 (1.90–5.49) p*† < 0.001 3.85 (1.50–8.13) p*† < 0.001
  CRP 0.66 (0.33–1.57) p*‡ = 0.074 1.03 (0.57–2.01) p*‡ = 0.267
IL6 (pg/ml) IL6* 1.35 (0.98–2.06)   1.61 (1.17–2.91)  
  IL6 2.48 (1.71–3.12) p*† = 0.002 3.30 (1.97–5.40) p*† < 0.001
  IL6 1.44 (0.97–1.93) p*‡ = 0.865 2.14 (1.23–2.82) p*‡ = 0.281
  1. Notes: IQR – interquartile range; p-values – differences tested by Wilcoxon test; *before surgery; 7–10 days after surgery; 28–30 days after surgery; p *†p-value of the difference between measurement before surgery and 7–10 days after surgery; p *‡p-value of the difference between measurement before surgery and 28–30 days after surgery