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Table 2 Hematological characteristics

From: Neutrophil-lymphocyte ratio predicts pathologic tumor response and survival after preoperative chemoradiation for rectal cancer

 

Pathologic response*

 
 

Good

Poor

 
 

Mean ± SD

Mean ± SD

P

Reference range

White blood cell

7 ± 2

7.9 ± 2

0.04

(4.0–10.0) × 109 /L

Neutrophil

4.1 ± 1.5

4.9 ± 1.7

0.01

(1.8–7.5) × 109 /L

Lymphocyte

2.1 ± 0.7

2.1 ± 0.7

0.96

(1.0–2.8) × 109 /L

Pre-CRT NLR

<3

33 (94.3%)

44 (65.7%)

0.001

 

≥3

2 (5.7%)

23 (34.3%)

  

Post-CRT NLR

<3

20 (57.1%)

31 (47.7%)

0.4

 

≥3

15 (42.9%)

34 (52.3%)

  

Platelet

275 ± 42

315 ± 113

0.2

(165–360) × 109 /L

C-reactive protein

0.4 ± 0.3

1.4 ± 2.7

0.03

<0.03 mg/dL

Albumin

4.2 ± 0.4

4 ± 0.5

0.2

(3.3-6.1) g/dL

mGPS

0

33 (94.3%)

58 (86.6%)

0.2

 
 

1,2

2 (5.7%)

9 (13.4%)

  
  1. *Good response group: complete pathologic response and ypTNM I, poor response group: ypTNM II,III and IV.
  2. SD, standard deviation; CRT, chemoradiation therapy; NLR, neutrophil-lymphocyte ratio; mGPS, modified Glasgow prognostic score.