Post-operative depletion of platelet count is associated with anastomotic insufficiency following intrahepatic cholangiojejunostomy: a case–control study from the results of 220 cases of intrahepatic cholangiojejunostomy

Table 1 Subject characteristics

Subject characteristics		Number of subjects
Age (years) median: 68	>68	126
Sex	Male/Female	146/74
Preoperative diagnosis	BDC	140
	GBC	35
	ICC	45
Body mass index; median: 22	<22	105
Diabetes mellitus	Positive	39
ICGR15 > 10%	Yes	129
ICGR15 > 15%	Yes	37
Preoperative biliary drainage	ENBD/PTBD	64/111
Preoperative albumin (g/dL); median: 3.8	<3.9	112
Preoperative portal vein embolism	Yes	114
Type of hepatectomy	Right	118
	Left	79
	Trisegmentectomy: Right/Left	10/11
	Other	2
Operative blood loss (mL); median: 1783	>1700	108
Operation time (min); median: 647	>660	154
Pancreaticoduodenectomy	Yes	30
Vascular combined resection	Hepatic artery	24
	Portal vein	118
Number of bile duct reconstructions; median: 3	≥3	139
Blood transfusion	Yes	84
Post-operative max AST (IU); median: 443	>440	110
Post-operative max ALT (IU); median: 372	>370	110
Platelet count (pre-operative period)	<12 × 10⁴/μL	6
Platelet count (post-operative day 1)	<10 × 10⁴/μL	30

BDC: extrahepatic cholangiocarcinoma, GBC: gallbladder cancer, ICC: intrahepatic cholangiocarcinoma, ICGR15: indocyanine green retention rate at 15 min, ENBD: endoscopic nasobiliary drainage, PTBD: percutaneous transhepatic biliary drainage, Right: right extended hepatectomy, Left: left extended hepatectomy, max: maximum, AST: aspartate aminotransferase, ALT: alanine aminotransferase.

ISSN: 1471-2482