Ultimate strength of extracellular matrix scaffolds subjected to infection. Ultimate strength (MPa) of small intestinal submucosa (SIS) and acellular human dermis (ADM) in response to inoculation with MRSA. White bars and black bars represent the control (non-inoculated) values for the 2 biologic meshes. Both materials exhibited the greatest reduction in ultimate strength at 20 days post inoculation. *Indicates a statistically significant difference between control groups. **Indicates a statistically significant difference between inoculated and control groups. Reproduced with permission from Bellows et al. .