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Table 2 Univariate analysis of prognostic factors of survival in patients with TE-SCC with CLM

From: Cervical lymph node metastasis classified as regional nodal staging in thoracic esophageal squamous cell carcinoma after radical esophagectomy and three-field lymph node dissection

  

5-year

Median survival

 

Variable

All (%)

Survival rate (%)

(Months)

χ2value

P- value

Patients

547 (100)

27.7

   

Sex

   

8.323

0.004

 Male

406 (74.2)

24.6

24.8

  

 Female

141 (25.8)

37.0

39.5

  

Age (years)

   

0.225

0.635

 <60

335 (61.2)

27.8

25.9

  

 ≥60

212 (38.8)

27.1

31.5

  

Thoracic tumor location

   

0.456

0.796

 Upper

121 (22.1)

31.7

29.2

  

 Middle

403 (73.7)

26.6

26.8

  

 Lower

23 (4.2)

23.3

25.5

  

Differentiation

   

1.623

0.444

 Low

118 (21.6)

23.4

24.1

  

 Intermediate

349 (63.8)

29.1

27.8

  

 High

80 (14.6)

28.6

28.3

  

Tumor length (cm)

   

7.638

0.006

 ≤5

283 (51.7)

31.7

32.0

  

 >5

264 (48.3)

23.4

23.6

  

pT stage

   

20.517

<0.0001

 pT1

16 (2.9)

86.7

53.6

  

 pT2

84 (15.4)

41.6

43.4

  

 pT3

386 (70.6)

23.1

26.4

  

 pT4

61 (11.2)

23.2

22.5

  

Number of nodal metastases

   

63.872

<0.0001

 1-2

226 (41.3)

43.3

49.7

  

 3-6

221 (40.4)

20.3

23.5

  

 ≥7

100 (18.3)

9.9

16.7

  

Number of fields with positive lymph nodesa

   

55.313

<0.0001

 1 field

191 (34.9)

43.0

43.3

  

 2 fields

214 (39.1)

25.5

29.2

  

 3 fields

142 (26.0)

10.2

19.3

  

Treatment program

   

18.145

<0.0001

 Surgery only

296 (54.1)

21.3

21.9

  

 Surgery + radiation

251 (45.9)

34.2

35.4

  
  1. Abbreviations: CLM cervical lymph node metastasis, TE-SCC thoracic esophageal squamous cell carcinoma.
  2. a1 field (cervical lymph nodes), 2 fields (cervical + mediastinal, and/or cervical + abdominal lymph nodes), 3 fields (cervical + mediastinal + abdominal lymph nodes) with positive lymph nodes.