The utility of the preoperative neutrophil-to-lymphocyte ratio in predicting severe cholecystitis: a retrospective cohort study

Table 3 Odds ratio for increased length of hospital stay (≥6 days; 80percentile) associated with clinical variables in patients undergoing cholecystectomy due to cholecystitis

	Univariate analysis			Multivariate analysis
	Odds ratio	95% C.I.	p-value	Odds ratio	95% C.I.	p-value
Age			< 0.001			< 0.001
< 50 years (standard)
≥ 50 years	2.553	1.642 – 3.970		2.312	1.472 – 3.630
Sex			0.036
Woman (standard)
Man	1.508	1.036 – 2.195
Body-mass index			1.000
< 25 (standard)
≥ 25	0.988	0.677 – 1.440
History of prior laparotomy			0.491
No (standard)
Yes	0.829	0.521 – 1.318
Preoperative leukocyte count (/mm³)			0.001
< 10,000 (standard)
≥ 10,000	1.928	1.307 – 2.844
Preoperative NLR			< 0.001			0.003
< 3.0 (standard)
≥ 3.0	2.482	1.696 – 3.633		1.876	1.246 – 2.825
Admission via ED			< 0.001			0.007
No (standard)
Yes	2.172	1.485 – 3.178		1.764	1.170 – 2.660
Approach of operative method^*			0.613
Conventional surgery
Reduced port surgery	0.892	0.602 – 1.321

Abbreviations: ED emergency department, NLR neutrophil-to-lymphocyte ratio.
*Conventional surgery included open surgery, 3-port and 4-port cholecystectomies, and reduced port surgery includes 2-port and single-port laparoscopic cholecystectomies.

ISSN: 1471-2482