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Table 1 Characteristics of 14,464 breast cancer patients# according to SSRI prescription.

From: Use of selective serotonin reuptake inhibitors and risk of re-operation due to post-surgical bleeding in breast cancer patients: a Danish population-based cohort study

Characteristics No SSRI Prescription
N (%)
Ever SSRI Prescription
N (%)
Total Population
N (%)
Age Group    
   <40 2010 (16) 147 (9) 2157 (15)
   40-49 2669 (21) 311 (20) 2980 (21)
   50-59 3117 (24) 373 (23) 3490 (24)
   60-69 2441 (19) 313 (20) 2754 (19)
   70-79 1699 (13) 258 (16) 1957 (14)
   > = 80 936 (7) 190 (12) 1126 (8)
Temporality of Anti-depressant (including SSRI, TCA, TeCA, others) Prescription    
   Never 11857 (92) 0 11857 (82)
   Current 266 (2) 411 (26) 677 (5)
   Former 749 (6) 1181 (74) 1930 (13)
Primary operation type    
   Breast-conserving surgery 7799 (61) 936 (59) 8735 (60)
   Mastectomy 5073 (39) 656 (41) 5719 (40)
Anti-depressant prescription    
   Never 11857 (92) 0 11857 (82)
   SSRI 0 1592 (100) 1592 (11)
   Tricyclic anti-depressants 526 (4) 0 526 (4)
   Tetracyclic anti-depressants 131 (1) 0 131 (1)
   Other 358 (3) 0 358 (3)
Oral Anti-coagulants prescription    
   No 12860 (99.9) 1589 (99.8) 14449 (99.9)
   Yes 12 (0.1) 3 (0.2) 15 (<0.1)
NSAIDs prescription    
   No 6134 (48) 493 (31) 6627 (46)
   Yes 6738 (52) 1099 (69) 7837 (54)
Aspirin prescription    
   No 12164 (95) 1423 (89) 13587 (94)
   Yes 708 (6) 169 (11) 877 (6)
Corticosteroid prescription    
   No 10969 (85) 1194 (75) 12163 (84)
   Yes 1903 (15) 398 (25) 2301 (16)
Vitamin K Antagonists Prescription    
   No 12599 (98) 1529 (96) 14128 (98)
   Yes 273 (2) 63 (4) 336 (2)
Platelet Inhibitors Prescription    
   None 11924 (93) 1341 (84) 13265 (92)
   Yes 948 (7) 251 (16) 1199 (8)
Comorbid diseases*    
   None 11764 (91) 1396 (88) 13160 (91)
   Yes 1108 (9) 196 (12) 1304 (9)
Comorbid Diseases    
   Liver disease 72 (0.6) 23 (1.4) 95 (0.7)
   Renal disease 89 (0.7) 27 (2) 116 (0.8)
   Cancer 951 (7) 141 (9) 1092 (8)
   Thrombocytopoenia 7 (0.05) 1 (0.06) 8 (0.06)
   Auto-immune disease 3 (0.02) 3 (0.02) 6 (0.04)
   Vascular disease 12 (0.1) 3 (0.2) 15 (<1)
  1. #Women diagnosed in Northern Denmark between 1996 and 2007 with complete prescription coverage since 1999.
  2. *Comorbid diseases includes liver disease, renal disease, uremia, cancer, thrombocytopoenia, auto-immunities, vasculitis
  3. SSRI = Selective serotonin reuptake inhibitors, TCA = Tricyclic anti-depressants, TeCA = Tetracyclic anti-depressants