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Table 2 Risk factors for intrahepatic recurrence after initial hepatectomy

From: Clinicopathological analysis of recurrence patterns and prognostic factors for survival after hepatectomy for colorectal liver metastasis

Factor

Number of patients

Univariate P-value

Multivariate P-value

Location of CRC

 

0.0733

 

Colon

27

  

Rectum

5

  

Depth of CRC

 

0.2112

 

< ss (a1)

19

  

> se (a2)

12

  

Tumor differentiation of CRC

 

0.4618

 

well

13

  

moderate

16

  

poor

1

  

Lymphatic invasion of CRC

 

1.0000

 

Present

25

  

Absent

5

  

Venous invasion of CRC

 

0.7765

 

Present

23

  

Absent

7

  

Lymph node metastasis of CRC

 

0.6320

 

Present

21

  

Absent

10

  

Time of liver metastasis

 

0.8151

 

Synchronous

12

  

Metachronous

20

  

Timing of hepatectomy

 

1.0000

 

Synchronous

6

  

Metachronous

26

  

Number of CRCLM

 

0.3516

 

Single

16

  

Multiple

16

  

Size of CRCLM

 

0.1218

 

< 5 cm

23

  

≥ 5 cm

8

  

Portal vein invasion of CRCLM

 

0.7072

 

Present

4

  

Absent

27

  

Surgical margin of CRCLM

 

0.0228

0.0133

< 5 mm

15

  

≥ 5 mm

13

  

Chemotherapy before hepatectomy

 

0.4837

 

Present

15

  

Absent

17

  

Chemotherapy after hepatectomy

 

0.1976

 

Present

19

  

Absent

12

  
  1. CRC: colorectal cancer, CRCLM: liver metastasis from colorectal cancer.