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Table 2 Gender specific adiponectin and leptin levels and resistin, MCP-1, active PAI-1, TNF-α, IL-1α, IL-6, IL-8, and IL-10 levels of septic patients (SP), morbidly obese (MO) and controls (BD).

From: Sepsis induced changes of adipokines and cytokines - septic patients compared to morbidly obese patients

Parameters
(normal values)
SP (n = 33)
(Median; range)
MO (n = 37)
(Median; range)
BD (n = 60)
(Median; range)
Change
SP vs. BD
Change
MO vs. BD
Adiponectin
(μg/ml)
10.3
(2.9 - 47.6)
9.4
(3.8 - 57.8)
14.7
(5.7 - 54.0)

p = < 0.01

p = < 0.01
Adiponectin male (μg/ml) 9.5
(2.9 - 32.6)
8.3
(3.8 - 12.3)
11.8
(5.7 - 30.7)

p = 0.04

p = < 0.01
Adiponectin female (μg/ml) 13.2
(5.3 - 47.6)
12.4
(5.3 - 57.8)
22.5
(9.8 - 54.0)

p = 0.02

p = < 0.01
Leptin (ng/ml) 6.3
(0.3 - 80.7)
45.0
(1.7 - 97.5)
10.8
(0.3 - 58.5)
no significant change
p = < 0.01
Leptin male (ng/ml)
(< 7 ng/ml)
6.3
(0.3 - 24.7)
34.2
(1.7 - 90.9)
4.6
(0.3 - 19.1)
no significant change
p = < 0.01
Leptin female (ng/ml)
(< 18 ng/ml)
8.2
(0.9 - 80.7)
47.3
(16.1 - 97.5)
15.8
(0.7 - 58.5)
no significant change
p = < 0.01
Resistin (ng/ml) 78.1
(13.4 - 52.3)
9.9
(3.7 - 83.6)
10.8
(5.2 - 24.9)

p = < 0.01
no significant change
MCP-1 (pg/ml) 381.5
(72.3 - 887.3)
108
(39.6 - 293)
43.9
(12.1 - 150)

p = < 0.01

p = < 0.01
Active PAI-1 (ng/ml) 35.9
(11.5 - 160.3)
57.5
(3.7 - 176.7)
6.0
(2.4 - 31.3)

p = < 0.01

p = < 0.01
TNF-α (pg/ml) 13.1
(2.4 - 65.5)
4.0
(2.4 - 26.8)
3.9
(1.2 - 10.9)

p = < 0.01
no significant change
IL-1α (pg/ml) 68.6
(9.2 - 203.3)
59.4
(9.2 - 210.0)
11.0
(9.2 - 168)

p = 0.04

p = 0.01
IL-6 (pg/ml) 163.6
(14.4 - 10000)
2.9
(0.9 - 64.2)
0.7
(0.4 - 568.6)

p = < 0.01

p = < 0.01
IL-8 (pg/ml) 59.4
(4.6 - 1335.6)
3.7
(0.3 - 38.8)
9.8
(0.9 - 126.7)

p = < 0.01

p = < 0.01
IL-10 (pg/ml) 26.7
(3.9 - 276.7)
2.5
(2.4 - 8.6)
1.2
(0.9 - 1038)

p = < 0.01

p = 0.01
  1. ↓↑: Significant increase/decrease;