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  1. This study was designed to identify risk factors for lymph node metastasis of early stage colorectal cancer, which was confirmed to a carcinoma that invaded the submucosa after radical resection.

    Authors: Bong-Hyeon Kye, Ji-Han Jung, Hyung-Jin Kim, Se-Goo Kang, Hyeon-Min Cho and Jun-Gi Kim
    Citation: BMC Surgery 2012 12:16
  2. The incision used for thyroid surgery has become shorter over time, from the classical 10 cm long Kocher incision to the shortest 15 mm access achieved with Minimally Invasive Video-Assisted Thyroidectomy. Thi...

    Authors: Fabrizio Consorti, Francesca Milazzo, Mariagiovanna Notarangelo, Laura Scardella and Alfredo Antonaci
    Citation: BMC Surgery 2012 12:15
  3. Patients having arthroscopic shoulder surgery frequently experience periods of inadvertent hypothermia. This common perioperative problem has been linked to adverse patient outcomes such as myocardial ischaemi...

    Authors: Jed Duff, Renatta Di Staso, Kerry-Anne Cobbe, Nicole Draper, Simon Tan, Emma Halliday, Sandy Middleton, Lawrence Lam and Kim Walker
    Citation: BMC Surgery 2012 12:14
  4. Hydrocephalus following spontaneous aneurysmal sub-arachnoid hemorrhage (SAH) is often associated with unfavorable outcome. This study aimed to determine the potential risk factors and outcomes of shunt-depend...

    Authors: Yi-Min Wang, Yu-Jun Lin, Ming-Jung Chuang, Tsung-Han Lee, Nai-Wen Tsai, Ben-Chung Cheng, Wei-Che Lin, Ben Yu-Jih Su, Tzu-Ming Yang, Wen-Neng Chang, Chih-Cheng Huang, Chia-Te Kung, Lian-Hui Lee, Hung-Chen Wang and Cheng-Hsien Lu
    Citation: BMC Surgery 2012 12:12
  5. To evaluate the quality of life (QOL) in relation to age, sex, clinical stage, postoperative complication, and adjuvant chemotherapy in patients who underwent curative total gastrectomy with D2 lymphadenectomy...

    Authors: Gintare Jakstaite, Narimantas Evaldas Samalavicius, Giedre Smailyte and Raimundas Lunevicius
    Citation: BMC Surgery 2012 12:11
  6. Hepaticojejunostomy (HJ) is the classical reconstruction for benign biliary stricture. Endoscopic management of anastomotic complications after hepaticojejunostomy is extremely difficult. In this work we asses...

    Authors: Mostafa A Hamad and Hussein El-Amin
    Citation: BMC Surgery 2012 12:9
  7. Communication breakdowns represent the main root cause of preventable complications which lead to harm to surgical patients. Standardized readbacks have been successfully implemented as a main pillar of profes...

    Authors: Hari Prabhakar, Jeffrey B Cooper, Allison Sabel, Sebastian Weckbach, Philip S Mehler and Philip F Stahel
    Citation: BMC Surgery 2012 12:8
  8. To describe the rationale and design of an observational cohort study analyzing the effects of endoscopic Totally Extraperitoneal (TEP) hernia repair on male fertility (MAIN study).

    Authors: Nelleke Schouten, Thijs van Dalen, Niels Smakman, Sjoerd G Elias, Cees van de Water, Roan J Spermon, Laurens Sibinga Mulder and Ine P J Burgmans
    Citation: BMC Surgery 2012 12:7
  9. Modern high-velocity projectiles produce temporary cavities and can thus cause extensive tissue destruction along the bullet path. It is still unclear whether gelatin blocks, which are used as a well-accepted ...

    Authors: Constantin von See, Majeed Rana, Marcus Stoetzer, Horst Kokemueller, Martin Ruecker and Nils-Claudius Gellrich
    Citation: BMC Surgery 2012 12:6
  10. Five percent of all patients with breast cancer have distant metastatic disease at initial presentation. Because metastatic breast cancer is considered to be an incurable disease, it is generally treated with ...

    Authors: Jetske Ruiterkamp, Adri C Voogd, Vivianne CG Tjan-Heijnen, Koop Bosscha, Yvette M van der Linden, Emiel JTh Rutgers, Epie Boven, Maurice JC van der Sangen and Miranda F Ernst
    Citation: BMC Surgery 2012 12:5
  11. Negative pressure wound therapy (NPWT) has gained acceptance among surgeons, for the treatment of open abdomen, since very high closure rates have been reported with this method, compared to other kinds of wou...

    Authors: Sandra Lindstedt, Malin Malmsjö, Johan Hansson, Joanna Hlebowicz and Richard Ingemansson
    Citation: BMC Surgery 2012 12:4
  12. Ultrasonic scalpel (UC) and monopolar electrocautery (ME) are common tools for soft tissue dissection. However, morphological data on the related tissue alteration are discordant. We developed an automatic dev...

    Authors: Kia Homayounfar, Johanna Meis, Klaus Jung, Bernd Klosterhalfen, Thilo Sprenger, Lena-Christin Conradi, Claus Langer and Heinz Becker
    Citation: BMC Surgery 2012 12:3
  13. A response to Seiler et al: Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg 20...

    Authors: Lars Fischer, Hanns P Knaebel, Henriette Golcher, Thomas Bruckner, Markus K Diener, Jeannine Bachmann, Markus W Büchler and Christoph M Seiler
    Citation: BMC Surgery 2012 12:2
  14. A beneficial effect of gentamicin supplemented mesh material on tissue integration is known. To further elucidate the interaction of collagen and MMP-2 in chronic foreign body reaction and to determine the sig...

    Authors: Marcel Binnebösel, Klaus T von Trotha, Christina Ricken, Christian D Klink, Karsten Junge, Joachim Conze, Marc Jansen, Ulf P Neumann and Petra Lynen Jansen
    Citation: BMC Surgery 2012 12:1
  15. To examine commonly used scoring systems, designed to predict overall outcome in critically ill patients, for their ability to select patients with an abdominal sepsis that have ongoing infection needing relap...

    Authors: Oddeke van Ruler, Jordy JS Kiewiet, Kimberley R Boer, Bas Lamme, Dirk J Gouma, Marja A Boermeester and Johannes B Reitsma
    Citation: BMC Surgery 2011 11:38
  16. Every surgical suture compresses the enclosed tissue with a tension that depends from the knotting force and the resistance of the tissue. The aim of this study was to identify the dynamic change of applied su...

    Authors: Christian D Klink, Marcel Binnebösel, Hamid P Alizai, Andreas Lambertz, Klaus T vonTrotha, Elmar Junker, Catherine Disselhorst-Klug, Ulf P Neumann and Uwe Klinge
    Citation: BMC Surgery 2011 11:36
  17. Peritoneal dialysis (PD) is an effective treatment for end-stage renal disease. It allows patients more freedom to perform daily activities compared to haemodialysis. Key to successful PD is the presence of a ...

    Authors: Sander M Hagen, Arjan M van Alphen, Jan NM IJzermans and Frank JMF Dor
    Citation: BMC Surgery 2011 11:35
  18. The CARTS study is a multicenter feasibility study, investigating the role of rectum saving surgery for distal rectal cancer.

    Authors: Guus MJ Bökkerink, Eelco JR de Graaf, Cornelis JA Punt, Iris D Nagtegaal, Heidi Rütten, Joost JME Nuyttens, Esther van Meerten, Pascal G Doornebosch, Pieter J Tanis, Eric J Derksen, Roy S Dwarkasing, Corrie AM Marijnen, Annemieke Cats, Rob AEM Tollenaar, Ignace HJT de Hingh, Harm JT Rutten…
    Citation: BMC Surgery 2011 11:34
  19. Anastomotic or marginal ulcers occur in 0.6 to 16% of patients after laparoscopic Roux-en-Y-Gastric Bypass. Initial therapy aims at eliminating known risk factors including smoking, Helicobacter pylori infecti...

    Authors: Daniel C Steinemann, Marc Schiesser, Pierre-Alain Clavien and Antonio Nocito
    Citation: BMC Surgery 2011 11:33
  20. Therapeutic strategies aiming to reduce ischemia/reperfusion injury by conditioning tissue tolerance against ischemia appear attractive not only from a scientific perspective, but also in clinics. Although pre...

    Authors: Robert Kraemer, Johan Lorenzen, Mohammad Kabbani, Christian Herold, Marc Busche, Peter M Vogt and Karsten Knobloch
    Citation: BMC Surgery 2011 11:32
  21. Accidental or intentional subcutaneous and/or intramuscular injection of metallic mercury is an uncommon form of poisoning. Although it does not carry the same risk as mercury vapour inhalation, it may cause d...

    Authors: Joerg Friesenbichler, Werner Maurer-Ertl, Patrick Sadoghi, Elisabeth Wolf and Andreas Leithner
    Citation: BMC Surgery 2011 11:31
  22. Many factors have been put forward as a driving mechanism of surgery-triggered adhesion formation (AF). In this study, we underline the key role of specific surgical trauma related with open surgery (OS) and l...

    Authors: Sergei V Pismensky, Zhomart R Kalzhanov, Marina Yu Eliseeva, Ioannis P Kosmas and Ospan A Mynbaev
    Citation: BMC Surgery 2011 11:30
  23. Degenerative spinal stenosis and instability requiring multilevel spine surgery has been associated with large blood losses. Factors that affect perioperative blood loss include time of surgery, surgical proce...

    Authors: Stefan Endres, Martin Heinz and Axel Wilke
    Citation: BMC Surgery 2011 11:29
  24. Obesity is a major public health problem in both developed and developing countries alike and leads to a series of changes in respiratory physiology. There is a strong correlation between obesity and cardiopul...

    Authors: Luis VF Oliveira, Isabella C Aguiar, Raquel P Hirata, Newton S Faria Junior, Israel S Reis, Luciana MM Sampaio, Claudia S Oliveira, Paulo TC Carvalho, Fernando SS Leitao Filho, Lilian C Giannasi, Lia Azevedo Pinto, Carlos Alberto Malheiros and Wilson Rodrigues Freitas Jr
    Citation: BMC Surgery 2011 11:28
  25. In the everyday surgical life, staff may experience that patients with Alcohol Use Disorders (AUDs) seem reluctant to participate in alcohol intervention programs. The objective was therefore to assess accepta...

    Authors: Bolette Pedersen, Kristian Oppedal, Lisa Egund and Hanne Tønnesen
    Citation: BMC Surgery 2011 11:26
  26. Mesh repair of incisional hernia is superior to the conventional technique. From all available materials for open surgery polypropylene (PP) is the most widely used. Development resulted in meshes with larger ...

    Authors: Roland Ladurner, Costanza Chiapponi, Quirin Linhuber and Thomas Mussack
    Citation: BMC Surgery 2011 11:25
  27. Emerging attempts have been made to reduce operative trauma and improve cosmetic results of laparoscopic cholecystectomy. There is a trend towards minimizing the number of incisions such as natural translumina...

    Authors: Daniel C Steinemann, Dimitri A Raptis, Georg Lurje, Christian E Oberkofler, Roland Wyss, Adrian Zehnder, Mickael Lesurtel, René Vonlanthen, Pierre-Alain Clavien and Stefan Breitenstein
    Citation: BMC Surgery 2011 11:24
  28. Research estimates of inadvertent harm to patients undergoing modern healthcare demonstrate a serious problem. Much attention has been paid to analysis of the causes of error and harm, but researchers have typ...

    Authors: Peter McCulloch and Ken Catchpole
    Citation: BMC Surgery 2011 11:23
  29. Hepatic resection is still associated with significant morbidity. Although the period of parenchymal transection presents a crucial step during the operation, uncertainty persists regarding the optimal techniq...

    Authors: Nuh N Rahbari, Heike Elbers, Moritz Koch, Thomas Bruckner, Patrick Vogler, Fabian Striebel, Peter Schemmer, Arianeb Mehrabi, Markus W Büchler and Jürgen Weitz
    Citation: BMC Surgery 2011 11:22
  30. Surgical site infection (SSI) continues to be a major source of morbidity and mortality in developing countries despite recent advances in aseptic techniques. There is no baseline information regarding SSI in ...

    Authors: Brian Mawalla, Stephen E Mshana, Phillipo L Chalya, Can Imirzalioglu and William Mahalu
    Citation: BMC Surgery 2011 11:21
  31. The median laparotomy is frequently used by abdominal surgeons to gain rapid and wide access to the abdominal cavity with minimal damage to nerves, vascular structures and muscles of the abdominal wall. Howeve...

    Authors: Joris J Harlaar, Eva B Deerenberg, Gabrielle H van Ramshorst, Harold E Lont, Ed CMH van der Borst, Willem R Schouten, Joos Heisterkamp, Helena C van Doorn, Huib A Cense, Frits Berends, Hein BAC Stockmann, Wietske W Vrijland, Esther CJ Consten, Reyer T Ottow, Peter MNYH Go, John J Hermans…
    Citation: BMC Surgery 2011 11:20
  32. Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for the management of biliary obstruction or leakage that results from a variety of benign and malignant diseases. Complications follo...

    Authors: Syed Nabeel Zafar, Muhammad Rizwan Khan, Rushna Raza, Muhammad N Khan, Mahwash Kasi, Ammar Rafiq and Omer H Jamy
    Citation: BMC Surgery 2011 11:19
  33. In the year 2000, the organizational structure of the ICU in the Zaandam Medical Centre (ZMC) changed from an open to a closed format ICU. The objective of this study was to evaluate the effect of this organiz...

    Authors: Frederik J van der Sluis, Cornelis Slagt, Barbara Liebman, Jan Beute, Jan WR Mulder and Alexander F Engel
    Citation: BMC Surgery 2011 11:18
  34. Colorectal cancer (CRC) is a major source of morbidity and mortality in the elderly population and surgery is often the only definitive management option. The suitability of surgical candidates based on age al...

    Authors: Muhammad Rizwan Khan, Hassaan Bari, Syed Nabeel Zafar and Syed Ahsan Raza
    Citation: BMC Surgery 2011 11:17
  35. Although liver resection has long been established for selected patients with benign hepatic disease, the success of surgical treatment of these patients cannot be evaluated exclusively through postoperative m...

    Authors: Carsten Kamphues, Sabine Engel, Timm Denecke, Roberta Bova, Michael Hippler-Benscheidt, Gero Puhl, Peter Neuhaus and Daniel Seehofer
    Citation: BMC Surgery 2011 11:16
  36. Various agents and techniques have been introduced to limit intra-operative blood loss from skin lesions. No uniformity regarding the type of haemostasis exists and this is generally based on the surgeon's pre...

    Authors: Marieke D Groenewold, Astrid J Gribnau and Dirk T Ubbink
    Citation: BMC Surgery 2011 11:15
  37. Upper gastrointestinal haemorrhage is mainly caused by ulcers. Gastric varicosis due to portal hypertension can also be held responsible for upper gastrointestinal bleeding. Portal hypertension causes the deve...

    Authors: Klaus T von Trotha, Marcel Binnebösel, Son Truong, Florian F Behrendt, Hermann E Wasmuth, Ulf P Neumann and Marc Jansen
    Citation: BMC Surgery 2011 11:14
  38. Adhesions are fibrous bands of scar tissue, often a result of surgery, that form between internal organs and tissues, joining them together abnormally. Postoperative adhesions frequently occur following abdomi...

    Authors: Vanja Sikirica, Bela Bapat, Sean D Candrilli, Keith L Davis, Malcolm Wilson and Alan Johns
    Citation: BMC Surgery 2011 11:13
  39. Enterocutaneous fistulas (ECF) are debilitating and usually result following complex abdominal surgery. While there is an association with inflammatory bowel disease (IBD), a large number of fistulas occur aft...

    Authors: Goher Rahbour, Ailsa L Hart, Hafid O Al-Hassi, Mohammad R Ullah, Simon M Gabe, Stella C Knight, Janindra Warusavitarne and Carolynne J Vaizey
    Citation: BMC Surgery 2011 11:12
  40. The presence of lymph node metastases remains the most reliable prognostic predictor and the gold indicator for adjuvant treatment in colon cancer (CC). In spite of a potentially curative resection, 20 to 30% ...

    Authors: Daniel J Lips, Boukje Koebrugge, Gerrit Jan Liefers, Johannes C van de Linden, Vincent THBM Smit, Hans FM Pruijt, Hein Putter, Cornelis JH van de Velde and Koop Bosscha
    Citation: BMC Surgery 2011 11:11
  41. Higher closure rates of the open abdomen have been reported with negative pressure wound therapy (NPWT) than with other wound management techniques. However, the method has occasionally been associated with in...

    Authors: Sandra Lindstedt, Malin Malmsjö, Johan Hansson, Joanna Hlebowicz and Richard Ingemansson
    Citation: BMC Surgery 2011 11:10
  42. Major colorectal surgery usually requires a hospital stay of more than 12 days. Inadequate pain management, intestinal dysfunction and immobilisation are the main factors associated with delay in recovery. The...

    Authors: José M Ramírez, Juan A Blasco, José V Roig, Sergio Maeso-Martínez, José E Casal, Fernando Esteban and Daniel Callejo Lic
    Citation: BMC Surgery 2011 11:9
  43. Breast-conserving surgery for breast cancer was developed as a method to preserve healthy breast tissue, thereby improving cosmetic outcomes. Thus far, the primary aim of breast-conserving surgery has been the...

    Authors: Nicole MA Krekel, Barbara M Zonderhuis, Hermien WH Schreurs, Alexander MF Lopes Cardozo, Herman Rijna, Henk van der Veen, Sandra Muller, Pieter Poortman, Louise de Widt, Wilfred K de Roos, Anne Marie Bosch, Annette HM Taets van Amerongen, Elisabeth Bergers, Mecheline HM van der Linden, Elly SM de Lange de Klerk, Henri AH Winters…
    Citation: BMC Surgery 2011 11:8
  44. Due to the increase of cardiovascular diseases acetylsalicylic acid (ASA) has become one of the most frequently prescribed drugs these days. Despite the rising number of patients with ASA medication presenting...

    Authors: Dalibor Antolovic, Christoph Reissfelder, Anastasia Rakow, Pietro Contin, Nuh N Rahbari, Markus W Büchler, Jürgen Weitz and Moritz Koch
    Citation: BMC Surgery 2011 11:7
  45. The myofibroblasts play a central role in wound healing throughout the body. The process of wound healing in the colon was evaluated with emphasis on the role of myofibroblasts.

    Authors: Christophoros Kosmidis, Christoforos Efthimiadis, Georgios Anthimidis, George Basdanis, Stylianos Apostolidis, Prodromos Hytiroglou, Kalliopi Vasiliadou, John Prousalidis and Epameinondas Fahantidis
    Citation: BMC Surgery 2011 11:6
  46. Adhesions formation is a significant postsurgical complication. At present, there is no effective method for preventing adhesions formation [1], although barrier products such as Dextran (Dex) [2] and sodium hyal...

    Authors: Qiang-Ye Zhang, Sheng Ma, Dong Xi, Wen-Tong Zhang and Ai-Wu Li
    Citation: BMC Surgery 2011 11:5

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