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  1. The importance of platelets in the pathogenesis of metastasis formation is increasingly recognized. Although evidence from epidemiologic studies suggests positive effects of aspirin on metastasis formation, th...

    Authors: E. Pretzsch, J. G. D’Haese, B. Renz, M. Ilmer, T. Schiergens, R. C. Miksch, M. Albertsmeier, M. Guba, M. K. Angele, J. Werner and H. Nieß
    Citation: BMC Surgery 2021 21:98
  2. Upper urinary tract urothelial carcinoma (UTUC) with multiple pathological types is extremely rare in the clinic, but the recurrence rate and mortality these patients are high. At present, there is no standard...

    Authors: Shangqing Ren, Hualin Feng, Yige Bao, Yi Wei, Yong Ou, Yaoqian Wang, Qian Lv, Shan Zhong, Fang Zhou, Shida Fan, Qiang Wang, Cheng Luo, Zhengjun Chen, Yu Nie and Dong Wang
    Citation: BMC Surgery 2021 21:96
  3. The hexapod external fixator (HEF) is increasingly used for high-energy tibial shaft fracture care as more general orthopedic surgeons are gaining expertise of this versatile device. The purpose of this study ...

    Authors: Yanshi Liu, Jialin Liu, Maimaiaili Yushan, Zhenhui Liu, Tao Zhang, He Ma, Chuang Ma and Aihemaitijiang Yusufu
    Citation: BMC Surgery 2021 21:95
  4. During clinical practice we have noticed that some patients with hyperthyroidism have finer skin with less wrinkles, pores, and spots after thyroidectomy, and the improvement can be observed within a few weeks...

    Authors: Spencer C. H. Kuo, Faye Huang, Shun-Yu Chi, Hui-Ping Lin, Peng-Chen Chien and Ching-Hua Hsieh
    Citation: BMC Surgery 2021 21:94
  5. Digitally designed surgical templates for minimally invasive temporomandibular joint (TMJ) surgery (MITMJS) are a promising tool for improving the safety of these procedures. Given the TMJ anatomy, the templat...

    Authors: Matthias Krause, Mohammad Kamal, Daniel Kruber, Dirk Halama, Thomas Hierl, Bernd Lethaus and Alexander K. Bartella
    Citation: BMC Surgery 2021 21:93
  6. Orbital solitary fibrous tumors (SFTs) are rare neoplasms. Recurrent, hypervascular, malignant variations of orbital SFTs have recently been noted and can present a surgical challenge.

    Authors: Xiawei Wang, Jianqin Shen, Hongguang Cui, Jianwei Pan, Xiaodong Teng, Min Yan, Shi Feng and Wei Ding
    Citation: BMC Surgery 2021 21:92
  7. The treatment of chronic pancreatitis requires a surgical approach in patients who are refractory to medical therapy. During surgical treatment, ductal decompression is required, but a pancreatectomy is necess...

    Authors: Kenta Saito, Yoichi Matsuo, Goro Ueda, Kan Omi, Yuichi Hayashi, Hiroyuki Imafuji, Ken Tsuboi, Mamoru Morimoto, Ryo Ogawa, Hiroki Takahashi, Itaru Naitoh, Kazuki Hayashi, Hiromi Kataoka and Shuji Takiguchi
    Citation: BMC Surgery 2021 21:91
  8. Primitive neuroectodermal tumours are clinically rare. Here, we report a case of a large peripheral primitive neuroectodermal tumour of the abdominal wall. The defect was reconstructed with the longest lateral...

    Authors: Xin Zhou, Pan You, Shuqing Huang, Xiang Li, Tongchun Mao, Anming Liu, Rongshuai Yan, Yiming Zhang, Wenlei Zhuo and Shaoliang Wang
    Citation: BMC Surgery 2021 21:90
  9. Mesenteric ischemia is associated with poor outcome and high overall mortality. The aim was to analyze an interdisciplinary treatment approach of vascular and visceral specialists focusing on the in-hospital o...

    Authors: Alicja Zientara, Anja-Rebeka Domenghino, Igor Schwegler, Hans Bruijnen, Annelies Schnider, Markus Weber, Stefan Gutknecht and Nicolas Attigah
    Citation: BMC Surgery 2021 21:89
  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Junsong Liu, Xiaoxia Wang, Rui Wang, Chongwen Xu, Ruimin Zhao, Honghui Li, Shaoqiang Zhang and Xiaobao Yao
    Citation: BMC Surgery 2021 21:85

    The original article was published in BMC Surgery 2020 20:4

  11. To explore the clinical safety and efficacy of single-stage posterior-only debridement, decompression, allograft bone using titanium mesh and interbody fusion combined for the treatment of thoracolumbar spinal...

    Authors: Wence Wu, Zhechen Li, Renqin Lin, Shenglin Wang and Jianhua Lin
    Citation: BMC Surgery 2021 21:84
  12. The gut microbiota (GM) has been proposed as one of the main determinants of colorectal surgery complications and theorized as the “missing factor” that could explain still poorly understood complications. Her...

    Authors: Annamaria Agnes, Caterina Puccioni, Domenico D’Ugo, Antonio Gasbarrini, Alberto Biondi and Roberto Persiani
    Citation: BMC Surgery 2021 21:83
  13. In recent years, natural orifice specimen extraction surgery (NOSES) has become a field of special interest for colorectal surgeons. Some researchers have reported transanal specimen extraction in the laparosc...

    Authors: Si Yu, Yong Ji, Tedong Luo, Pengjie Xu, Zuojun Zhen and Jianzhong Deng
    Citation: BMC Surgery 2021 21:82
  14. The prognostic value of external vs internal pancreatic duct stents after pancreaticoduodenectomy remains controversial. This study aimed to evaluate the benefits of external and internal stents using the Fist...

    Authors: Yuancong Jiang, Qin Chen, Yi Shao, Zhenzhen Gao, Ming Jin, Bingqiang Gao, Bo Zhou and Sheng Yan
    Citation: BMC Surgery 2021 21:81
  15. The occurrence of postoperative ileus leads to increased patient morbidity, longer hospitalization, and higher healthcare costs. No clear policy on postoperative ileus prevention exists. Therefore, we aim to e...

    Authors: Yosuke Namba, Yuzo Hirata, Shoichiro Mukai, Sho Okimoto, Seiji Fujisaki, Mamoru Takahashi, Toshikatsu Fukuda and Hideki Ohdan
    Citation: BMC Surgery 2021 21:80
  16. At present, the term mucocele is outdated, and mucinous appendiceal neoplasm is preferred. Mucinous appendiceal neoplasm is an uncommon pathology that occurs predominantly in middle-aged women. Its classificat...

    Authors: Belén Matias-García, Fernando Mendoza-Moreno, Ana Blasco-Martínez, José Ignacio Busteros-Moraza, Manuel Diez-Alonso and Francisca Garcia-Moreno Nisa
    Citation: BMC Surgery 2021 21:79
  17. The radical antegrade modular pancreatosplenectomy (RAMPS) which is a reasonable surgical approach for left-sided pancreatic cancer is emphasis on the complete resection of regional lymph nodes and tumor-free ...

    Authors: Ren-Chao Zhang, Xin-Jun Gan, Wei Song, Song-Tao Shi, Hui-Fang Yu and Yi-Ping Mou
    Citation: BMC Surgery 2021 21:78
  18. We compared the advantages and disadvantages of modified triangular anastomosis and tubular anastomosis for digestive tract reconstruction in patients undergoing laparoscopic-assisted radical resection of righ...

    Authors: Tianfang Xia, Zhenguo Pan, Jie Zhang and Guo Xu
    Citation: BMC Surgery 2021 21:77
  19. Angular pregnancy is characterized as implant medial to the uterotubal junction in lateral angular of uterine. It was a rare obstetric complication with severe complications like uterine rupture and retained p...

    Authors: Yin Meichen, Fei Jing, Zhai Lingyun and Zhou Jianwei
    Citation: BMC Surgery 2021 21:76
  20. Knot tying technique is an extremely important basic skill for all surgeons. Clinically, knot slippage or suture breakage will lead to wound complications. Although some previous studies described the knot-tyi...

    Authors: Kengo Harato, Mitsuru Yagi, Kazuya Kaneda, Yu Iwama, Akihiko Masuda, Yosuke Kaneko, Akihito Oya, Noboru Matsumura, Taku Suzuki, Robert Nakayama and Shu Kobayashi
    Citation: BMC Surgery 2021 21:75
  21. Intestinal failure (IF) is a rare but severe form of organ failure. The condition is defined as body’s inability to absorb adequate fluids, macronutrients and minerals for growth and development, so that intra...

    Authors: Kiarash Ashrafzadeh, Mojtaba Shafiekhani, Nazanin Azadeh, Maryam Esmaeili and Hamed Nikoupour
    Citation: BMC Surgery 2021 21:73
  22. Most hepatocellular carcinoma (HCC) patients’ liver function indexes are abnormal. We aimed to investigate the relationship between (alkaline phosphatase + gamma-glutamyl transpeptidase)/lymphocyte ratio (AGLR...

    Authors: Yan Liao, Rongyu Wei, Renzhi Yao, Liling Qin, Jun Li, Junxiong Yu and Weijia Liao
    Citation: BMC Surgery 2021 21:72
  23. The present study aims to assess the preliminary outcomes of the effectiveness of wrapping the ligamentum teres hepatis (LTH) around the gastroduodenal artery stump for the prevention of erosion hemorrhage aft...

    Authors: Lingwei Meng, He Cai, Yunqiang Cai, Yongbin Li and Bing Peng
    Citation: BMC Surgery 2021 21:70
  24. Elective implant removal (IR) after fracture fixation is one of the most common procedures within (orthopedic) trauma surgery. The rate of surgical site infections (SSIs) in this procedure is quite high, espec...

    Authors: Fay R K Sanders, Diederick Penning, Manouk Backes, Siem A Dingemans, Susan van Dieren, Anne M Eskes, J Carel Goslings, Peter Kloen, Ron A A Mathôt, Niels W L Schep, Ingrid J B Spijkerman and Tim Schepers
    Citation: BMC Surgery 2021 21:69
  25. The role of laparoscopic adrenalectomy (LA) in a large adrenal tumor is controversial due to the risk of malignancy and technical difficulty. In this study, we compared the perioperative outcomes and complicat...

    Authors: Thanasit Prakobpon, Apirak Santi-ngamkun, Manint Usawachintachit, Supoj Ratchanon, Dutsadee Sowanthip and Kamol Panumatrassamee
    Citation: BMC Surgery 2021 21:68
  26. Congenital primary inguinal hernia is a common condition among children. Although much literature regarding inguinal hernia is available, large scale analysis are few, and rarely do they expand on gender diffe...

    Authors: Kai Wang, Sarah Siyin Tan, Yue Xiao, Zengmeng Wang, Chunhui Peng, Wenbo Pang, Dongyang Wu and Yajun Chen
    Citation: BMC Surgery 2021 21:67
  27. Perianal/perineal rhabdomyosarcomas (PRMS) are easily misdiagnosed soft tissue tumours with a poor prognosis. This study was designed to analyze the clinical, diagnostic, pathological and prognostic features o...

    Authors: Yaoyu Guo, Bang Hu, Dandan Huang, Xinhua Wang, Juan Li, Di Zhang, Xueying Li, Gong Chen and Donglin Ren
    Citation: BMC Surgery 2021 21:66
  28. Percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) have been widely used to treat neurologically intact osteoporotic Kümmell’s disease (KD), but it is still unclear which treatment is more advantageous. O...

    Authors: Shou-qian Dai, Rong-qing Qin, Xiu Shi and Hui-lin Yang
    Citation: BMC Surgery 2021 21:65
  29. In hospitalized patients, abnormal plasma electrolyte concentrations are frequent and have been linked to poor outcomes following acute surgery. The aim of this study was to assess whether preoperative plasma ...

    Authors: Mohamed Ebrahim, Pia Bükmann Larsen, Damoun Hannani, Sara Liest, Lars Nannestad Jørgensen and Henrik Løvendahl Jørgensen
    Citation: BMC Surgery 2021 21:62
  30. Oral and maxillofacial surgery specialty has grown rapidly in Kuwait in recent years. However, the general public and healthcare professionals remain unaware of its expanding scope of practice. The aim of the ...

    Authors: Mohammad Kamal, Mohammad Abdulwahab and Ahmed Al-Zaid
    Citation: BMC Surgery 2021 21:61
  31. To date, the evidence on the safety and benefits of minimally invasive pancreatoduodenectomy (MIPD) in elderly patients is still controversy. This study aim to compare the risk and benefit between MIPD and ope...

    Authors: Shih-Min Yin, Yueh-Wei Liu, Yu-Yin Liu, Chee-Chien Yong, Chih-Chi Wang, Wei-Feng Li and Cheng-Hsi Yeh
    Citation: BMC Surgery 2021 21:60
  32. Gallbladder cancer is a rare but highly malignant cancer, which often progresses to a metastatic stage when diagnosed because of its asymptomatic manifestation. In this study, we intended to analyze the progno...

    Authors: Yingnan Yang, Zhuolong Tu, Chentao Ye, Huajie Cai, Shouzhang Yang, Xuehai Chen and Jinfu Tu
    Citation: BMC Surgery 2021 21:59
  33. Endoscopic endonasal transsphenoidal approaches are broadly used nowadays for a vast spectrum of pathologies sited in the anterior and middle cranial fossa. The usage of neuronavigation systems (neuronavigatio...

    Authors: Vlastimil Novák, Lumír Hrabálek, Jan Valošek, Jakub Jablonský, Jiří Hoza, Ivona Korčáková, Martin Hampl, Přemysl Stejskal and Csaba Hučko
    Citation: BMC Surgery 2021 21:58
  34. To determine the standard remnant liver volume (SRLV) threshold to avoid postoperative hepatic insufficiency inpatients in different stages of hepatic fibrosis who undergo right hemi-hepatectomy.

    Authors: Zhiming Zhang, Gaoxiong Ouyang, Peng Wang, Yuan Ren, Yukai Liu, Jun Chen, Yumei Zhang, Jianyong Liu and Lequn Li
    Citation: BMC Surgery 2021 21:57
  35. Synchronous multicentric osteosarcoma (SMOS) is a rare disease characterized by simultaneous multicentricity of intraosseous osteosarcoma without visceral involvement. SMOS, including a skull lesion, which occ...

    Authors: Yoshihiro Araki, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Takayuki Nojima and Hiroyuki Tsuchiya
    Citation: BMC Surgery 2021 21:56
  36. There are few articles about the surgical techniques of thalamic glioma and the lesions in the basal ganglia area. According to three existing cases and the literature review (Twelve articles were summarized w...

    Authors: Haiyang Yang, Gang Bai, Yongli Zhang, Guolong Chen, Lei Duan, Youyun Bi and Haifeng Yang
    Citation: BMC Surgery 2021 21:55
  37. Surgeons are likely to get progressively fatigued during the course of a normal workday. The objective of this study was to evaluate the impact of surgeon work duration prior to performing distal pancreatectom...

    Authors: Zhen Wan, Xuzhen Wang, Yong Li and Renhua Wan
    Citation: BMC Surgery 2021 21:54
  38. To investigate the association between postoperative lymph nodes (LNs) recurrence and distinct serum thyroglobulin (Tg) levels in patients with papillary thyroid carcinoma (PTC).

    Authors: Zhichao Xing, Yuxuan Qiu, Zhe Li, Lingyun Zhang, Yuan Fei, Jingqiang Zhu and Anping Su
    Citation: BMC Surgery 2021 21:53
  39. The treatment of defects on the volar surface of the finger has been scarcely reported, and its utility for digital resurfacing remains unclear. This study compared the outcomes of free medial plantar artery f...

    Authors: Quanzhe Liu, Wenlai Guo, Wenrui Qu, Xiaolan Ou, Rui Li and Heng Tian
    Citation: BMC Surgery 2021 21:52
  40. Most evidence regarding lateral lymph node dissection for rectal cancer is from expert settings. This study aimed to evaluate the safety and efficacy of this procedure in a practice-based cohort.

    Authors: Masakatsu Numata, Hiroshi Tamagawa, Keisuke Kazama, Shinnosuke Kawahara, Sho Sawazaki, Toru Aoyama, Yukio Maezawa, Kazuki Kano, Akio Higuchi, Teni Godai, Yusuke Saigusa, Hiroyuki Saeki, Norio Yukawa and Yasushi Rino
    Citation: BMC Surgery 2021 21:51
  41. Gastrointestinal lymphomas like diffuse large B-cell lymphoma (DLBCL) are rare complications of ulcerative colitis (UC), and only a few studies have reported intestinal ulcers caused by DLBCL, which got perfor...

    Authors: Takafumi Suzuki, Kazutsugu Iwamoto, Ryoichi Nozaki, Yasumitsu Saiki, Masafumi Tanaka, Mitsuko Fukunaga and Kazutaka Yamada
    Citation: BMC Surgery 2021 21:50
  42. To evaluate the use of a human fibrin glue (Tisseel) for minor bleeding control and approximation of ovarian defect during transvaginal natural orifice ovarian cystectomy (TNOOC) of benign and non-endometrioti...

    Authors: Yu-Ying Su, Yu-Shan Lin, Lan-Yan Yang, Yu-Bin Pan, Yi-Ting Huang, Cindy Hsuan Weng, Kai-Yun Wu and Chin-Jung Wang
    Citation: BMC Surgery 2021 21:49

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