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Table 4 Univariable and multivariable analyses to determine independent predictors of postoperative complications of primary retroperitoneal sarcoma

From: Development and validation of a nomogram for predicting morbidity in surgically resected primary retroperitoneal sarcoma

Variables

Univariate analysis

Multivariate analysis

Hazard ratio (95%CI)

P value

Hazard ratio (95%CI)

P value

Gender male vs. female

1.394 (0.892–2.177)

0.145

  

Age > 65 vs ≤ 65 years

1.927 (1.137–3.265)

0.015

1.836 (0.999–3.374)

0.050

ASA score > 1 vs. 1

1.372 (0.855–2.201)

0.190

  

Symptoms yes vs. no

1.032 (0.659–1.615)

0.891

  

Tumor burden > 10 vs ≤ 10 cm

3.378 (1.961–5.819)

 < 0.001

1.786 (0.930–3.430)

0.081

Histologic subtypes

 

0.046

 

0.314

 DDLPS vs. WDLPS

1.239 (0.704–2.180)

 

0.698 (0.350–1.394)

 

 LMS vs. WDLPS

0.393 (0.191–0.808)

 

0.682 (0.270–1.722)

 

 SFT vs. WDLPS

0.786 (0.327–1.886)

 

1.143 (0.454–2.876)

 

 Others vs. WDLPS

0.707 (0.340–1.471)

 

2.012 (0.683–5.931)

 

FNCLCC

 

0.636

  

 Grade 2 vs. Grade 1

1.198 (0.698–2.057)

   

 Grade 3 vs. Grade 1

1.239 (0.709–2.167)

   

 Unknown vs. Grade 1

0.567 (0.143–2.251)

   

Location left vs. right

1.092 (0.700–1.703)

0.698

  

Multifocality yes vs. no

1.515 (0.721–3.183)

0.273

  

Radiation yes vs. no

0.750 (0.321–1.752)

0.506

  

Chemotherapy yes vs. no

1.025 (0.504–2.084)

0.946

  

Operation laparoscopic vs. open

0.267 (0.031–2.314)

0.231

  

Complete Resection yes vs. no

1.377 (0.391–4.854)

0.619

  

Number of combined resections > 1 vs. 0–1

2.576 (1.628–4.074)

 < 0.001

2.864 (1.261–6.507)

0.012

Weighted resected organ score (continuous)

1.894 (1.563–2.296)

 < 0.001

2.041 (1.454–2.865)

 < 0.001

Operative time > 4 vs. ≤ 4 h

5.088 (2.994–8.646)

 < 0.001

2.074 (1.064–4.043)

0.032

Estimated blood loss > 400 vs. ≤ 400 ml

4.109 (2.560–6.595)

 < 0.001

1.594 (0.807–3.150)

0.179

Packed RBC transfusion yes vs. no

1.315 (1.163–1.487)

 < 0.001

1.726 (0.888–3.357)

0.108

ICU Stay yes vs. no

2.669 (1.687–4.221)

 < 0.001

1.259 (0.661–2.396)

0.484

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