Skip to main content

Table 6 Univariate and multivariate Cox regression analyses of disease free survival in 372 elderly patients after curative resection

From: The safety and prognosis of radical surgery in colorectal cancer patients over 80 years old

Variables

Disease free survival

Univariate analysis

Multivariate analysis

HR(95%CI)

P

HR(95%CI)

P

Gender: male/female

1.42 (1.01–1.99)

0.046

1.28 (0.90–1.82)

0.171

Age at operation: ≥ 85/ < 85

1.69 (0.82–3.45)

0.152

1.31 (0.62–2.75)

0.480

ASA score: III/II

1.01 (0.72–1.43)

0.939

  

Body mass index: ≥ 24/ < 24

0.46 (0.32–0.66)

 < 0.001

0.56 (0.37–0.85)

0.046

Preoperative albumin: ≥ 35/ < 35

1.85 (1.17–2.93)

0.008

1.38 (0.85–2.23)

0.190

Preoperative HGB: ≥ 110/ < 110

1.37 (0.87–2.14)

0.175

1.30 (0.81–2.10)

0.281

Habits: drinking

0.95 (0.61–1.47)

0.811

  

Habits: smoking

1.11 (0.72–1.69)

0.640

  

Comorbity: yes/no

1.27 (0.89–1.81)

0.188

1.17 (0.81–1.69)

0.397

Previous abdominal surgery: yes/no

1.24 (0.83–1.87)

0.293

  

Tumor location

    

 Left colon

Reference

  

 Right colon

0.99 (0.63–1.57)

0.968

  

 Rectum

0.95 (0.64–1.42)

0.802

  

Surgical procedure: open/laparoscope

0.96 (0.68–1.36)

0.813

  

Operative time: ≥ 135/ < 135

1.20 (0.83–1.73)

0.338

  

T stage: T3-T4/T1-T2

1.05 (0.69–1.60)

0.816

  

N stage: N1-N2/N0

0.35 (0.24–0.50)

 < 0.001

0.51 (0.34–0.76)

 < 0.001

Tumor grade

    

 I

Reference

  

 II

2.36 (1.14–4.86)

0.020

1.85 (0.87–3.92)

0.109

 III

3.38 (1.54–7.41)

0.002

2.26 (0.99–5.15)

0.053

Perineural invasion: yes/no

2.07 (1.41–3.03)

0.211

  

Lymphatic invasion

1.07 (0.73–1.56)

0.729

  

Grade 3–4 complications: yes/no

0.63 (0.41–0.98)

0.040

0.85 (0.53–1.35)

0.483

Re-operation: yes/no

1.24 (0.39–3.88)

0.718