From: The safety and prognosis of radical surgery in colorectal cancer patients over 80 years old
Variables | Disease free survival | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR(95%CI) | P | HR(95%CI) | P | |
Gender: male/female | 1.42 (1.01–1.99) | 0.046 | 1.28 (0.90–1.82) | 0.171 |
Age at operation: ≥ 85/ < 85 | 1.69 (0.82–3.45) | 0.152 | 1.31 (0.62–2.75) | 0.480 |
ASA score: III/II | 1.01 (0.72–1.43) | 0.939 | ||
Body mass index: ≥ 24/ < 24 | 0.46 (0.32–0.66) | < 0.001 | 0.56 (0.37–0.85) | 0.046 |
Preoperative albumin: ≥ 35/ < 35 | 1.85 (1.17–2.93) | 0.008 | 1.38 (0.85–2.23) | 0.190 |
Preoperative HGB: ≥ 110/ < 110 | 1.37 (0.87–2.14) | 0.175 | 1.30 (0.81–2.10) | 0.281 |
Habits: drinking | 0.95 (0.61–1.47) | 0.811 | ||
Habits: smoking | 1.11 (0.72–1.69) | 0.640 | ||
Comorbity: yes/no | 1.27 (0.89–1.81) | 0.188 | 1.17 (0.81–1.69) | 0.397 |
Previous abdominal surgery: yes/no | 1.24 (0.83–1.87) | 0.293 | ||
Tumor location | ||||
Left colon | Reference | – | ||
Right colon | 0.99 (0.63–1.57) | 0.968 | ||
Rectum | 0.95 (0.64–1.42) | 0.802 | ||
Surgical procedure: open/laparoscope | 0.96 (0.68–1.36) | 0.813 | ||
Operative time: ≥ 135/ < 135 | 1.20 (0.83–1.73) | 0.338 | ||
T stage: T3-T4/T1-T2 | 1.05 (0.69–1.60) | 0.816 | ||
N stage: N1-N2/N0 | 0.35 (0.24–0.50) | < 0.001 | 0.51 (0.34–0.76) | < 0.001 |
Tumor grade | ||||
I | Reference | – | ||
II | 2.36 (1.14–4.86) | 0.020 | 1.85 (0.87–3.92) | 0.109 |
III | 3.38 (1.54–7.41) | 0.002 | 2.26 (0.99–5.15) | 0.053 |
Perineural invasion: yes/no | 2.07 (1.41–3.03) | 0.211 | ||
Lymphatic invasion | 1.07 (0.73–1.56) | 0.729 | ||
Grade 3–4 complications: yes/no | 0.63 (0.41–0.98) | 0.040 | 0.85 (0.53–1.35) | 0.483 |
Re-operation: yes/no | 1.24 (0.39–3.88) | 0.718 |