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Table 4 Univariate and multivariate Cox regression analyses of cancer specific survival in 372 elderly patients after curative resection

From: The safety and prognosis of radical surgery in colorectal cancer patients over 80 years old

Variables

Cancer specific survival

Univariate analysis

Multivariate analysis

HR(95%CI)

P

HR(95%CI)

P

Gender: male/female

1.63 (0.88–3.02)

0.118

1.18 (0.60–2.29)

0.636

Age at operation: ≥ 85/ < 85

1.84 (0.83–4.08)

0.137

1.57 (0.65–3.83)

0.317

ASA score: III/II

1.08 (0.62–1.90)

0.779

  

Body mass index

    

 < 24

Reference

-

Reference

-

 ≥ 24

1.76 (1.01–3.05)

0.046

2.30 (1.27–4.17)

0.006

Preoperative albumin: ≥ 35/ < 35

0.74 (0.40–1.35)

0.322

  

Preoperative HGB: ≥ 110/ < 110

0.63 (0.34–1.19)

0.158

0.70 (0.35–1.42)

0.326

Habits: drinking

1.46 (0.79–2.70)

0.233

  

Habits: smoking

1.49 (0.83–2.69)

0.184

1.55 (0.80–3.00)

0.193

Comorbity: yes/no

0.78 (0.45–1.36)

0.382

  

Previous abdominal surgery:yes/no

0.69 (0.33–1.48)

0.342

  

Tumor location: left colon and rectum/ right colon

1.09 (0.58–2.04)

0.797

  

Surgical procedure: open/laparoscope

1.46 (0.83–2.57)

0.185

1.20 (0.65–2.22)

0.564

Operative time: ≥ 135/ < 135

1.12 (0.65–1.94)

0.688

  

T stage: T3-T4/T1-T2

2.28 (0.97–5.35)

0.058

1.34 (0.54–3.35)

0.528

N stage: N1-N2/N0

2.90 (1.63–5.18)

 < 0.001

2.97 (1.48–5.97)

0.002

Tumor grade

    

 I

Reference

-

  

 II

0.71 (0.28–1.83)

0.483

  

 III

0.94 (0.33–2.67)

0.904

  

Perineural invasion: yes/no

1.74 (0.95–3.19)

0.074

1.19 (0.59–2.42)

0.627

Lymphatic invasion

1.99 (1.14–3.47)

0.016

1.03 (0.53–1.98)

0.939

Grade 3–4 complications: yes/no

0.82 (0.35–1.92)

0.641

  

Re-operation: yes/no

3.21 (0.77–13.37)

0.109

1.67 (0.35–8.03)

0.523