From: The safety and prognosis of radical surgery in colorectal cancer patients over 80 years old
Variables | Cancer specific survival | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR(95%CI) | P | HR(95%CI) | P | |
Gender: male/female | 1.63 (0.88–3.02) | 0.118 | 1.18 (0.60–2.29) | 0.636 |
Age at operation: ≥ 85/ < 85 | 1.84 (0.83–4.08) | 0.137 | 1.57 (0.65–3.83) | 0.317 |
ASA score: III/II | 1.08 (0.62–1.90) | 0.779 | ||
Body mass index | ||||
< 24 | Reference | - | Reference | - |
≥ 24 | 1.76 (1.01–3.05) | 0.046 | 2.30 (1.27–4.17) | 0.006 |
Preoperative albumin: ≥ 35/ < 35 | 0.74 (0.40–1.35) | 0.322 | ||
Preoperative HGB: ≥ 110/ < 110 | 0.63 (0.34–1.19) | 0.158 | 0.70 (0.35–1.42) | 0.326 |
Habits: drinking | 1.46 (0.79–2.70) | 0.233 | ||
Habits: smoking | 1.49 (0.83–2.69) | 0.184 | 1.55 (0.80–3.00) | 0.193 |
Comorbity: yes/no | 0.78 (0.45–1.36) | 0.382 | ||
Previous abdominal surgery:yes/no | 0.69 (0.33–1.48) | 0.342 | ||
Tumor location: left colon and rectum/ right colon | 1.09 (0.58–2.04) | 0.797 | ||
Surgical procedure: open/laparoscope | 1.46 (0.83–2.57) | 0.185 | 1.20 (0.65–2.22) | 0.564 |
Operative time: ≥ 135/ < 135 | 1.12 (0.65–1.94) | 0.688 | ||
T stage: T3-T4/T1-T2 | 2.28 (0.97–5.35) | 0.058 | 1.34 (0.54–3.35) | 0.528 |
N stage: N1-N2/N0 | 2.90 (1.63–5.18) | < 0.001 | 2.97 (1.48–5.97) | 0.002 |
Tumor grade | ||||
I | Reference | - | ||
II | 0.71 (0.28–1.83) | 0.483 | ||
III | 0.94 (0.33–2.67) | 0.904 | ||
Perineural invasion: yes/no | 1.74 (0.95–3.19) | 0.074 | 1.19 (0.59–2.42) | 0.627 |
Lymphatic invasion | 1.99 (1.14–3.47) | 0.016 | 1.03 (0.53–1.98) | 0.939 |
Grade 3–4 complications: yes/no | 0.82 (0.35–1.92) | 0.641 | ||
Re-operation: yes/no | 3.21 (0.77–13.37) | 0.109 | 1.67 (0.35–8.03) | 0.523 |