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Table 2 Comparison of clinicopathological factors and recurrence sites in R0 and R1 cases

From: Indications for resection of recurrent lesions in patients with distal cholangiocarcinoma based on prognostic factors: a single-institute retrospective study and brief literature review

Variables

R0 (n = 75)

R1 (n = 26)

p-value

CEA (ng/mL), median (range)

3.2 (1.2–14.4)

4.0 (1.6–11.9)

0.099

CA19-9 (U/mL), median (range)

48.4 (1.0–4815.2)

58.2 (10.8–1253.5)

0.255

Gross type (Papillary)

20 (26.7)

2 (7.7)

0.034

Primary tumour size (mm), median (range)

20 (1–70)

31 (7–90)

0.001

Pancreatic invasion (positive)

34 (45.3)

18 (69.2)

0.030

Duodenal invasion (positive)

11 (14.7)

6 (23.1)

0.242

Portal vein invasion (positive)

0

4 (15.4)

0.004

Lymphovessel invasion (positive)

54 (72.0)

19 (73.1)

0.566

Vascular invasion (positive)

43 (57.3)

18 (69.2)

0.202

Perineural invasion (positive)

55 (73.3)

25 (96.2)

0.009

pT3

36 (48.0)

23 (88.5)

< 0.001

pN1

21 (28.0)

11 (44.0)

0.135

Tumour differentiation (Well)

44 (58.7)

15 (57.7)

0.555

Recurrence site

 Local

7 (9.3)

11 (42.3)

< 0.001

 Liver

12 (16.0)

3 (11.5)

0.423

 Lung

3 (4.0)

1 (3.8)

0.728

 Peritoneum

3 (4.0)

2 (7.7)

0.383

 Lymph node

2 (2.7)

0

0.550

 Multiple

5 (6.7)

3 (11.5)

0.344

  1. CEA carcinoembryonic antigen