Skip to main content

Table 6 Univariate and multivariate analyses of risk factors for overall morbidity and mortality in patients with biliary obstruction (n = 120)

From: The effect of preoperative biliary drainage on postoperative complications of pancreaticoduodenectomy: a triple center retrospective study

Characteristics

Overall morbidity

Mortality

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Age

1.015 (0.983–1.048)

0.357

  

1.018 (0.980–1.058)

0.349

  

Male gender

1.029 (0.465–2.277)

0.943

  

0.801 (0.319–2.013)

0.637

  

Stent placement

1.962 (0.927–4.153)

0.078

0.229 (0.050–1.037)

0.056

0.593 (0.247–1.423)

0.242

  

Symptoms

        

 Duration

0.999 (0.995–1.002)

0.419

  

1.000 (0.995–1.004)

0.956

  

 Abdominal pain

0.798 (0.301–2.116)

0.650

  

1.650 (0.472–5.766)

0.433

  

 Weight loss

1.034 (0.404–2.647)

0.945

  

0.904 (0.292–2.804)

0.862

  

 Malaise

0.862 (0.313–2.370)

0.773

  

1.618 (0.492–5.320)

0.428

  

 Nausea/vomiting

4.861 (1.014–23.296)

0.048

5.215 (0.522–52.122)

0.160

0.224 (0.027–1.847)

0.164

  

 Fever

0.703 (0.174–2.842)

0.621

  

2.000 (0.448–8.936)

0.364

  

Medical history

 Diabetes

0.933 (0.374–2.329)

0.882

  

0.700 (0.214–2.285)

0.555

  

 Hypertension

0.513 (0.222–1.185)

0.118

  

1.554 (0.583–4.140)

0.378

  

 Coronary artery disease

1.552 (0.447–5.388)

0.489

  

0.306 (0.038–2.486)

0.268

  

 Thyroid disease

0.984 (0.158–6.143)

0.987

  

2.867 (0.449–18.308)

0.266

  

 Neoadjuvant therapy

0.516 (0.156–2.714)

0.401

  

2.932 (0.611–14.071)

0.179

  

 ASA score > 2

1.167 (0.535–2.544)

0.697

  

1.051 (0.422–2.613)

0.916

  

Preop lab

        

 WBC

1.000 (1.000–1.000)

0.501

  

1.000 (1.000–1.000)

0.343

  

 Lymphopenia

4.065 (0.456–36.255)

0.209

  

0.796 (0.085–7.447)

0.842

  

 Total bilirubin

0.953 (0.911–0.998)

0.039

1.013 (0.934–1.097)

0.759

1.039 (0.998–1.093)

0.134

  

 Alkaline phosphatase

1.000 (0.999–1.000)

0.608

  

1.000 (0.999–1.001)

0.908

  

 Albumin

1.514 (0.588–3.900)

0.391

  

1.231 (0.421–3.604)

0.704

  

 Total protein

0.923 (0.418–2.036)

0.843

  

4.679 (0.952–23.004)

0.058

3.931 (0.058–266.177)

0.524

 Creatinine

4.730 (0.475–47.094)

0.185

  

0.524 (0.034–8.110)

0.644

  

Histopathology

        

 Tumor size

1.286 (0.843–1.964)

0.243

  

0.826 (0.507–1.348)

0.445

  

Operation

        

 Harvested LNs

0.994 (0.931–1.062)

0.861

  

1.033 (0.959–1.112)

0.391

  

 Estimated blood loss

0.999 (0.998–1.000)

0.023

0.999 (0.996–1.002)

0.369

1.001 (1.000–1.002)

0.053

1.004 (0.990–1.017)

0.620

 Surgery duration

0.997 (0.994–1.000)

0.023

1.000 (0.991–1.009)

0.977

1.004 (1.000–1.007)

0.029

0.995 (0.950–1.042)

0.830

  1. Bold p-values represent p-values <0.05
  2. WBC white blood cells, LN lymph node