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Table 5 Univariate and multivariate analyses of risk factors for overall morbidity and mortality in all patients (n = 147)

From: The effect of preoperative biliary drainage on postoperative complications of pancreaticoduodenectomy: a triple center retrospective study

Characteristics

Overall morbidity

Mortality

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Age

1.004 (0.976–1.032)

0.796

  

1.028 (0.993–1.064)

0.117

  

Male gender

1.000 (0.497–2.012)

1.000

  

0.957 (0.418–2.193)

0.917

  

Stent placement

1.625 (0.832–3.174)

0.156

  

0.674 (0.303–1.502)

0.334

  

Symptoms

        

 Duration

0.999 (0.996–1.003)

0.623

  

0.999 (0.995–1.004)

0.789

  

 Jaundice

0.447 (0.137–1.458)

0.182

  

2.500 (0.535–11.692)

0.244

  

 Abdominal pain

1.028 (0.421–2.512)

0.951

  

1.365 (0.437–4.261)

0.592

  

 Weight loss

0.834 (0.349–1.995)

0.683

  

1.185 (0.413–3.400)

0.752

  

 Malaise

0.704 (0.274–1.814)

0.468

  

2.037 (0.672–6.171)

0.208

  

 Nausea/vomiting

4.286 (0.913–20.126)

0.065

4.726 (0.534–41.834)

0.163

0.238 (0.029–1.934)

0.179

  

 Fever

0.595 (0.149–2.377)

0.463

  

2.265 (0.514–9.970)

0.280

  

Medical history

 Diabetes

0.838 (0.352–1.991)

0.688

  

0.674 (0.212–2.144)

0.504

  

 Hypertension

0.610 (0.282–1.317)

0.208

  

1.556 (0.626–3.865)

0.341

  

 Coronary artery disease

1.270 (0.409–3.948)

0.679

  

0.622 (0.131–2.942)

0.549

  

 Thyroid disease

0.817 (0.175–3.804)

0.796

  

1.750 (0.320–9.567)

0.518

  

 Neoadjuvant therapy

0.650 (0.156–2.714)

0.555

  

2.446 (0.549–10.900)

0.241

  

 ASA score > 2

0.839 (0.411–1.713)

0.631

  

1.670 (0.726–3.842)

0.228

  

Preop lab

        

 WBC

1.000 (1.000–1.000)

0.306

  

1.000 (1.000–1.000)

0.122

  

 Lymphopenia

2.667 (0.521–13.655)

0.239

  

1.250 (0.230–6.786)

0.796

  

 Total bilirubin

0.952 (0.911–0.994)

0.026

0.966 (0.907–1.030)

0.294

1.043 (0.994–1.094)

0.089

1.072 (0.981–1.171)

0.126

 Alkaline phosphatase

1.000 (0.999–1.000)

0.408

  

1.000 (0.999–1.001)

0.941

  

 Albumin

1.574 (0.661–3.748)

0.305

  

0.792 (0.291–2.154)

0.648

  

 Total protein

0.809 (0.387–1.691)

0.574

  

2.979 (0.900–9.865)

0.074

3.191 (0.890–11.449)

0.075

 Creatinine

1.084 (0.243–4.833)

0.916

  

2.372 (0.452–12.452)

0.307

  

Histopathology

 Tumor size

1.304 (0.933–1.822)

0.120

  

0.798 (0.535–1.188)

0.266

  

Operation

        

 Harvested LNs

0.998 (0.940–1.059)

0.938

  

1.026 (0.958–1.100)

0.461

  

 Estimated blood loss

0.999 (0.998–1.000)

0.015

0.999 (0.996–1.001)

0.346

1.001 (1.000–1.002)

0.105

  

 Surgery duration

0.997 (0.994–0.999)

0.008

1.001 (0.993–1.009)

0.783

1.002 (1.000–1.005)

0.106

  
  1. Bold p-values represent p-values <0.05
  2. WBC white blood cells, LN lymph node
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