Table 1 Patients’ characteristics
All non-resected | Exploration only | Biliary bypass | Gastroenteric bypass | Double bypass | P-value | |
|---|---|---|---|---|---|---|
n = 389/389 (100%) | n = 127/389 (32.6%) | n = 92/389 (23.7%) | n = 65/389 (16.7%) | n = 105/389 (27.0%) | ||
Age, median [IQR] | 68 [60 to 75] | 66 [57 to 74] | 69 [58 to 77] | 67 [61 to 76] | 69 [63 to 74] | 0.452 |
Sex | 0.088 | |||||
Female | 163 (41.9%) | 48 (37.8%) | 48 (52.2%) | 22 (33.8%) | 45 (42.9%) | |
Male | 226 (58.1%) | 79 (62.2%) | 44 (47.8%) | 43 (66.2%) | 60 (57.1%) | |
BMI, median [IQR], kg/m2 | 24.2 [21.8 to 27.1] | 24.0 [21.6 to 26.8] | 25.2 [22.6 to 28.1] | 23.6 [21.7 to 25.8] | 24.1 [21.3 to 27.8] | 0.059 |
Biliary stent | 114 (29.3%) | 21 (16.5%) | 37 (40.2%) | 17 (26.2%) | 39 (37.1%) | 0.0002 |
ASA | 0.186 | |||||
1 | 4 (1.0%) | – | – | 1 (1.5%) | 3 (2.9%) | |
2 | 145 (37.3%) | 47 (37.0%) | 37 (40.2%) | 20 (30.8%) | 41 (39.0%) | |
3 | 231 (59.4%) | 78 (61.4%) | 55 (59.8%) | 41 (63.1%) | 57 (54.3%) | |
4 | 9 (2.3%) | 2 (1.6%) | – | 3 (4.6%) | 4 (3.8%) | |
Localization | < 0.0001 | |||||
Head | 313 (80.5%) | 81 (63.8%) | 87 (94.6%) | 49 (75.4%) | 96 (91.4%) | |
Body | 54 (13.9%) | 31 (24.4%) | 5 (5.4%) | 11 (16.9%) | 7 (6.7%) | |
Tail | 18 (4.6%) | 15 (11.8%) | – | 2 (3.1%) | 1 (1.0%) | |
Other | 4 (1.0%) | – | – | 3 (4.6%) | 1 (1.0%) | |
Liver metastases | ||||||
Present | 140 (36.0%) | 48 (37.8%) | 31 (33.7%) | 25 (38.5%) | 36 (34.3%) | 0.658 |
Absent | 204 (52.4%) | 62 (48.8%) | 55 (59.8%) | 31 (47.7%) | 56 (53.3%) | |
Unknown | 45 (11.6%) | 17 (13.4%) | 6 (6.5%) | 9 (13.8%) | 13 (12.4%) | |
Bilirubin, median [IQR], mg/dl | 1.3 [0.6 to 9.0] | 0.7 [0.4 to 2.7] | 4.1 [0.8 to 12.3] | 0.9 [0.5 to 1.6] | 3.3 [0.9 to 10.8] | < 0.0001 |
Elevated (> 1.1 mg/dl) | 202 (51.9%) | 42 (33.1%) | 63 (68.5%) | 24 (36.9%) | 73 (69.5%) | < 0.0001 |
Normal (≤ 1.1 mg/dl) | 177 (45.5%) | 81 (63.8%) | 29 (31.5%) | 38 (58.5%) | 29 (27.6%) | |
Unknown | 10 (2.6%) | 4 (3.1%) | – | 3 (4.6%) | 3 (2.9%) | |
CA19-9, median [IQR], U/ml | 384 [73 to 1421] | 375 [66 to 1756] | 426 [92 to 999] | 327 [53 to 1340] | 380 [96 to 1406] | 0.967 |
Elevated (> 37 U/ml) | 268 (68.9%) | 89 (70.1%) | 71 (77.2%) | 42 (64.6%) | 66 (62.9%) | 0.898 |
Normal (≤ 37 U/ml) | 59 (15.2%) | 22 (17.3%) | 13 (14.1%) | 9 (13.8%) | 15 (14.3%) | |
Unknown | 62 (15.9%) | 16 (12.6%) | 8 (8.7%) | 14 (21.5%) | 24 (22.9%) | |
CEA, median [IQR], ng/ml | 4.2 [2.3 to 10.5] | 4.0 [2.0 to 10.6] | 4.6 [2.9 to 10.6] | 4.6 [2.5 to 12.5] | 4.2 [2.0 to 7.9] | 0.702 |
Elevated (> 5 ng/dl) | 115 (29.6%) | 46 (36.2%) | 29 (31.5%) | 18 (27.7%) | 22 (21.0%) | 0.723 |
Normal (≤ 5 ng/dl) | 159 (40.9%) | 57 (44.9%) | 43 (46.7%) | 21 (32.3%) | 38 (36.2%) | |
Unknown | 115 (29.6%) | 24 (18.9%) | 20 (21.7%) | 26 (40.0%) | 45 (42.9%) |