Table 4 The demographic and clinicopathological data of patients with/without ectopic ACTH syndrome
Factor | Patients with ectopic ACTH syndrome | Patients without ectopic ACTH syndrome | P |
|---|---|---|---|
Number | 22 | 20 | |
Sex, female, n (%) | 8 (36.4) | 7 (35) | P = 0.927 |
Age, median (IQR) | 34.5 (29.3, 45) | 59 (49.3, 65) | P = 0.007 |
Pathological result | |||
Typical, n (%) | 17 (77.3) | 7 (35.0) | P = 0.047 |
Atypical, n (%) | 5 (22.7) | 13 (65.0) | |
Surgical procedure | P = 0.847 | ||
Segmentectomy, n (%) | 2 (9.1) | 0 | |
Lobectomy, n (%) | 20 (90.9) | 14 (70.0) | |
Bilobectomy, n (%) | 0 | 3 (15.0) | |
Sleeve, n (%) | 0 | 3 (15.0) | |
Tumor size, median (IQR) | 1.5 (1, 2) | 4.8 (2.8, 4.1) | P = 0.003 |
T1 ≤ 3 cm, n (%) | 22 (100) | 6 (30) | |
T2 > 3 cm, ≤ 5 cm, n (%) | 0 | 10 (50) | |
T3 > 5 cm, ≤ 7 cm, n (%) | 0 | 4 (20) | |
T4 > 7 cm, n (%) | 0 | 0 | |
Nodes metastases | P = 0.385 | ||
N1 positive, n (%) | 7 (41.7) | 9 (45) | |
N2 positive, n (%) | 15 (58.3) | 11 (55) | |
Ki-67, median (IQR) | 2.5 (2, 3.75) | 7.5 (5, 11.25) | P = 0.001 |
Chemotherapy | |||
Yes, n (%) | 5 (37.5) | 13 (50) | P = 0.047 |
No, n (%) | 17 (62.5) | 7 (50) | |