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Table 5 Risk factors for local residual cancer

From: Evaluation of additional gastrectomy after noncurative endoscopic submucosal dissection for early gastric cancer

 

Local RC Positive

Local RC Negative

Univariate

Multivariate

 
 

(n = 7)

(n = 93)

P-Value

OR (95% CI)

P

Tumor size

     

   ≤ 30 mm

1

63

 

Reference

 

  > 30 mm

6

30

0.008

176.00 (0.92–33,800.00)

0.054

Depth of invasion

     

  M-SM1

2

18

   

  SM2 or deeper

5

75

0.625

  

Histological type

     

  Differentiated

6

75

   

  Undifferentiated

1

18

1.000

  

Ulceration

     

  Negative

3

79

 

Reference

 

  Positive

4

14

0.019

16.00 (0.99–259.00)

0.051

Lymphatic invasion

     

  Negative

2

55

 

Reference

 

  Positive

5

38

0.136

22.80 (0.61–860.00)

0.091

Vascular invasion

     

  Negative

6

72

   

  Positive

1

21

1.000

  

Horizontal margin

     

  Negative

4

90

 

Reference

 

  Positive

3

3

0.004

71.30 (2.83–1790.00)

0.010

Vertical margin

     

  Negative

4

77

 

Reference

 

  Positive

3

16

0.124

21.50 (0.82–564.00)

0.066

  1. RC residual cancer, M confined to mucosa, SM1 depth of invasion from the muscularis mucosa < 500 µm
  2. SM2 depth of invasion from the muscularis mucosa ≥ 500 µm, OR odds ratio, CI confidence interval