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Table 1 Demographic data, complications and lactate etiology

From: Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors

Parameter

Total

Survivors

Non-survivors

pa

n = 239

n = 42 (17.6%)

n = 197 (82.4%)

Mean age (years) ± SD

67.6 ± 12.3

64.1 ± 13.5

68.3 ± 12.0

< 0.001

Gender

 Male

144 (60.3%)

23 (9.6%)

121 (50.6%)

0.264

 Female

95 (39.7%)

19 (7.9%)

76 (31.8%)

 

Mean duration of ICU stay (days)

10.1 ± 13.8

14.4 ± 13.4

9.2 ± 13.7

0.025*

Hospitalization days (days)

20.6 ± 23.7

37.2 ± 25.8

17.0 ± 21.7

0.000*

Ventilation [n (percentage)]

208 (87.0%)

30 (12.6%)

178 (74.5%)

0.004*

Renal replacement [n (percentage)]

72 (30.1%)

11 (4.6%)

61 (25.5%)

0.340

Maximum lactate (mmol/L)

17.0 ± 5.8

13.9 ± 4.4

17.8 ± 5.8

0.001*

Lactate etiology*

 Sepsis

124 (51.9%)

14 (11.3%)

110 (88.7%)

 

 Mesenteric ischemia

36 (15.1%)

5 (13.9%)

31 (86.1%)

 

 Hemorrhagic shock

33 (13.8%)

8 (24.2%)

25 (75.8%)

 

 Liver failure

23 (9.6%)

7 (30.4%)

16 (69.6%)

 

 Cardiopulmonary resuscitation

12 (5.0%)

2 (16.7%)

10 (83.3%)

 

 Cardiogenic shock

6 (2.5%)

2 (33.3%)

4 (66.7%)

 

 Seizure

2 (0.8%)

1 (50%)

1 (50%)

 

 Other reasons

3 (1.3%)

3 (100%)

0 (0%)

 
  1. Mann–Whitney-U-Test
  2. aFor lactate etiology/ Fisher’s exact Test for other parameters
  3. * Significant difference between groups regardings Fisher's exact test