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Table 4 Predictive ability of the optimal cut off values on the risk of early recurrence

From: Preoperative and postoperative nomograms for predicting early recurrence of hepatocellular carcinoma without macrovascular invasion after curative resection

Variables

Preoperative nomogram

Postoperative nomogram

Training cohort (482)

Validation cohort (216)

Training cohort (482)

Validation cohort (216)

AUC

0.721 (0.684–0.759)

0.754 (0.690–0.817)

0.848 (0.814–0.883)

0.844 (0.790–0.897)

Cut-off score

88

88

110

110

Sensitivity

0.611 (0.567–0.654)

0.642 (0.578–0.706)

0.706 (0.665–0.747)

0.679 (0.617–0.741)

Specificity

0.716 (0.676–0.756)

0.76 (0.703–0.817)

0.802 (0.766–0.838)

0.800 (0.746–0.853)

Positive predictive value

0.704 (0.663–0.745)

0.77 (0.714–0.826)

0.793 (0.756–0.829)

0.764 (0.707–0.821)

Negative predictive value

0.587 (0.543–0.631)

0.629 (0.565–0.693)

0.724 (0.684–0.764)

0.699 (0.638–0.760)

Positive likelihood ratio

2.151 (2.011–2.291)

2.675 (2.393–2.957)

3.564 (3.294–3.834)

3.394 (3.014–3.774)

Negative likelihood ratio

0.543 (0.499–0.587)

0.471 (0.404–0.538)

0.367 (0.324–0.411)

0.401 (0.336–0.466)

  1. CI: confidence interval