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Table 3 Univariate and multivariate Cox regression analyses of 5-year OS

From: Albumin/fibrinogen ratio, a predictor of chemotherapy resistance and prognostic factor for advanced gastric cancer patients following radical gastrectomy

 

Univariate Multivariate

Variables

HR (95%CI)

P value

 

HR (95%CI)

P value

Age (≥ 48 vs. < 48)

1.18 (0.48–2.90)

0.684

   

Cycles of chemotherapy (≥ 3 vs. < 3)

1.47 (1.06–2.17)

0.041

 

1.34(0.65–3.27)

0.341

Tumor size (≥ 4.85 vs. < 4.85)

0.65 (0.23–1.74)

0.403

   

Tumor differentiation (moderately/well vs. poor)

2.26 (1.03–5.03)

0.008

 

2.07 (1.11–4.01)

0.022

Clinical TNM stage (III vs. II)

0.44 (0.22–0.91)

0.013

 

0.28 (0.09–0.81)

0.029

AFR (< 10.85 vs. ≥ 10.85)

0.18 (0.05–0.53)

0.002

 

0.36 (0.15–0.73)

0.011

CEA (≥ 5.0 vs. < 5.0)

1.24 (0.45–3.43)

0.652

   

CA19–9 (≥ 40 vs. < 40)

1.14 (0.48–2.81)

0.776

   
  1. OS overall survival, AFR albumin/fibrinogen ratio, CEA carcinoembryonic antigen, CA cancer antigen, HR hazard ratio, CI confidence interval