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Table 2 Preoperative laboratory tests associated with chemotherapeutic resistance in GC patients

From: Albumin/fibrinogen ratio, a predictor of chemotherapy resistance and prognostic factor for advanced gastric cancer patients following radical gastrectomy

 

Chemotherapeutic resistance

 

Patient characteristics

No (n = 119)

Yes (n = 41)

P-value

Hb (mg/dL)

13.0 ± 1.8

12.9 ± 1.9

0.763a

WBC (×109/L)

7.5 ± 2.2

7.4 ± 1.9

0.796a

Platelet (×109/L)

199.5 ± 32.4

191.1 ± 30.3

0.148b

Cr (mg/dL)

0.84 ± 0.13

0.81 ± 0.13

0.204a

Urea(mmol/L)

6.4 ± 1.2

6.5 ± 1.4

0.660a

AFR

11.8 ± 2.2

10.7 ± 2.0

0.001a*

CEA (ng/ml)

0.029c*

≥ 5.0

7 (5.9)

7 (17.1)

< 5.0

112 ( 94.1)

34 (82.9)

CA19–9 (kU/L)

0.034c*

≥ 40

11 (9.2)

9 (22.0)

< 40

108 (91.8)

32 (78.0)

CA72–4 (U/mL)

0.525d

≥ 6

8 (6.7)

4 (9.8)

< 6

111 (93.3)

37 (90.2)

CA125 (U/ml)

0.437d

≥ 35

6 (5.0)

4 (9.8)

 

< 35

113 (95.0)

45 (90.2)

  1. Hb hemoglobin, WBC white blood cell, Cr creatinine, AFR albumin/fibrinogen ratio, CEA carcinoembryonic antigen, CA cancer antigen. *P value < 0.05. aStudent t test, bMann Whitney U test, cChi-square test, dFisher exact test