Category | Characteristic | No postoperative therapy (n = 370/55.9%) | Postoperative (chemo-)radiotherapy (n = 291/44.1%) | Total (n = 661) |
---|---|---|---|---|
General | Age (years) | 57.3 ± 11.0 [15.7–91.6] | 56.7 ± 8.8 [37.8–82.3] | 57.0 ± 10.1 [15.7–91.6] |
Gender (male/female) | 312 (84.3%)/58 (15.7%) | 246 (84.5%)/45 (15.5%) | 558 (84.4%)/103 (15.6%) | |
Follow up (months) | 82.0 ± 53.3 [1.1–263.3] | 68.0 ± 53.7 [0.3–252.8] | 75,8 ± 53.9 [0.3–263.3] | |
Tumor origin | Oral cavity | 78 (21.1%) | 57 (19.6%) | 135 (20.4%) |
Oropharynx | 65 (17.6%) | 114 (39.2%) | 179 (27.1%) | |
Hypopharynx | 51 (13.8%) | 67 (23.0%) | 118 (17.8%) | |
Larynx | 176 (47.6%) | 53 (18.2%) | 229 (34.6%) | |
Tumor side | bilateral | 90 (24.3%) | 67 (23.0%) | 157 (23.8%) |
midline | 18 (4.9%) | 6 (2.0%) | 24 (3.6%) | |
right | 139 (37.6%) | 116 (39.9%) | 255 (38.6%) | |
left | 123 (33.2%) | 102 (35.0%) | 225 (34.0%) | |
Tumor category | pT1 | 60 (16.2%) | 26 (8.9%) | 86 (13.0%) |
pT2 | 136 (36.8%) | 72 (24.7%) | 208 (31.5%) | |
pT3 | 126 (34.1%) | 113 (38.8%) | 239 (36.2%) | |
pT4 | 48 (13.0%) | 80 (27.5%) | 128 (19.4%) | |
clinical Lymph Node Status | cN0 | 202 (54.6%) | 60 (20.6%) | 262 (39.6%) |
cN1 | 62 (16.8%) | 49 (16.8%) | 111 (16.8%) | |
cN2 | 85 (23.0%) | 161 (55.3%) | 246 (37.2%) | |
cN3 | 0 (0.0%) | 5 (1.7%) | 5 (0.8%) | |
cNx | 21 (5.7%) | 16 (5.5%) | 37 (5.6%) | |
pathological Lymph Node Status | pN0 | 258 (69.7%) | 44 (15.1%) | 302 (45.7%) |
pN1 | 59 (15.9%) | 60 (20.6%) | 119 (18.0%) | |
pN2 | 53 (14.3) | 187 (64.3%) | 240 (36.3%) | |
Distant metastasis during follow-up | M0 | 353 (95.4%) | 247 (84.9%) | 600 (90.8%) |
M1 | 17 (4.6%) | 44 (15.1%) | 61 (9.2%) | |
Ipsilateral Neck Dissection | any | 359 (97.0%) | 283 (97.3%) | 642 (97.1%) |
Level I | 69 (18.6%) | 51 (17.2%) | 120 (18.2%) | |
Level II | 356 (96.2%) | 257 (88.3%) | 613 (92.7%) | |
Level III | 349 (94.3%) | 256 (88.0%) | 605 (91.5%) | |
Level IV | 64 (17.3%) | 76 (26.1%) | 140 (21.2%) | |
Level V | 9 (2.4%) | 17 (5.8%) | 26 (3.9%) | |
Contralateral Neck dissection | Any | 175 (40.6%) | 144 (49.5%) | 319 (48.3%) |
Level I | 34 (9.2%) | 20 (6.9%) | 54 (8.2%) | |
Level II | 171 (46.2%) | 142 (48.8%) | 313 (47.4%) | |
Level III | 168 (45.4%) | 141 (48.5%) | 309 (46.7%) | |
Level IV | 23 (6.2%) | 32 (11.0%) | 55 (8.3%) | |
Level V | 3 (0.8%) | 4 (1.4%) | 7 (1.1%) |