Table 2 Clinicopathological characteristics of pN1 patients based on NMLNs
Clinicopathological characteristics | NMLNs ≤ 5 n = 472 | NMLNs > 5 n = 222 | Total n = 694 | P value |
|---|---|---|---|---|
Age (years) | Â | Â | Â | Â |
 Mean | 44.0 | 37.0 |  |  < 0.001* |
  < 55 | 389/472 (82.4) | 196/222 (88.3) | 585 | 0.047* |
   ≥ 55 | 83/472 (17.6) | 26/222 (11.7) | 109 | |
Sex | Â | Â | Â | 0.093 |
 Female | 344/472 (72.9) | 148/222 (66.7) | 492 | |
 Male | 128/472 (27.1) | 74/222 (33.3) | 202 | |
Tumor size (mm) | Â | Â | Â | Â |
 Mean | 9.0 | 14.0 |  |  < 0.001* |
  ≤ 10 | 260/472 (55.1) | 69/222 (31.1) | 329 |  < 0.001* |
  10–20 | 164/472 (34.7) | 103/222 (46.4) | 267 | |
  20–40 | 40/472 (8.5) | 43/222 (19.4) | 83 | |
  > 40 | 8/472 (1.7) | 7/222 (3.1) | 15 | |
Bilaterality |  |  |  |  < 0.001* |
 Present | 142/472 (30.1) | 110/222 (49.5) | 252 | |
 Absent | 330/472 (69.9) | 112/222 (50.5) | 442 | |
Multifocality |  |  |  |  < 0.001* |
 Present | 185/472 (39.2) | 120/222 (54.1) | 305 | |
 Absent | 287/472 (60.8) | 102/222 (45.9) | 389 | |
ETE |  |  |  |  < 0.001* |
 Present | 360/472 (76.3) | 205/222 (92.3) | 565 | |
 Absent | 112/472 (23.7) | 17/222 (7.7) | 129 | |
TNM stage | Â | Â | Â | 0.032* |
 I | 389/472 (82.4) | 197/222 (88.7) | 586 | |
 II | 83/472 (17.6) | 25/222 (11.3) | 108 | |
HT | Â | Â | Â | 0.935 |
 Present | 67/472 (14.2) | 31/222 (14.0) | 98 | |
 Absent | 405/472 (85.8) | 191/222 (86.0) | 596 | |
BRAF V600E mutation | Â | Â | Â | 0.166 |
 Positive | 46/55 (83.6) | 22/31 (71.0) | 68 | |
 Negative | 9/55 (16.4) | 9/31 (29.0) | 18 |