Effect of radical lymphadenectomy in colorectal cancer with para-aortic lymph node metastasis: a systematic review and meta-analysis

Table 1 Characteristic of included clinical studies

Study	Types of studies	NO. of patients	Intervention		Primary endpoint	Synchronous or Metachronous	Country	Location of tumor
Study	Types of studies	NO. of patients	Treatment group	Comparison group	Primary endpoint	Synchronous or Metachronous	Country	Location of tumor
Lee, S. C. et al., 2021	CCS	73	Dissection	Non-dissection	5-year OS	Synchronous	Korea	All
Lee, J. et al., 2021	CS	19	R0 resection	R2 resection	5-year OS	No instructions	Korea	Left-sided
Ichikawa, Y. et al., 2021	CS	28	Radical resections	Targeted dissections	3-year RFS	Both (16:12)	Japan	All
Sahara, K. et al., 2019	CCS	62	R0 resection	R1/R2 resection	5-year OS	Synchronous	Japan	Left-sided
Nakai, N. et al., 2017	CCS	30	R0 resection	R1/R2 resection	5-year OS	Both (16:14)	Japan	Left-sided
Choi, P. W. et al., 2010	CCS	77	Dissection	Non-dissection	5-year OS	Both (19:5)	Korea	All
Byung, S. M. et al., 2008	CCS	38	Dissection	Non-dissection	5-year OS	Metachronous	Korea	All

CS cohort study, CCS case–control study, OS overall survival, RFS recurrence‐free survival, NOS the Newcastle–Ottawa Scale

ISSN: 1471-2482