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Table 7 Multivariate analysis of risk factors for postoperative morbidity and severe morbidity in patients received lobectomy

From: Analysis of risk factors for postoperative complications in non-small cell lung cancer: comparison with the Japanese National Clinical Database risk calculator

Postoperative morbidity

Variables

 

Odds ratio

95% CI

P value

Comorbidity

Chronic renal failure

4.82

0.809–28.755

0.08

 

Asthma

4.18

1.291–13.556

0.01

Smoking status

Brinkman index ≥ 600

1.45

0.930–2.266

0.10

CEA

 > 5

1.37

0.878–2.156

0.16

PNI

 < 49.68

1.40

0.921–2.130

0.11

NLR

 > 1.56

1.49

0.903–2.477

0.11

FEV1%

 < 70

1.30

0.828–2.051

0.25

Operative procedure

RUL or RLL or LUL

2.21

1.277–3.823

 < 0.01

Postoperative severe morbidity

Sex

Man

2.35

1.152–4.818

0.01

BMI

 ≥ 22.93

2.41

1.277–4.550

 < 0.01

%VC

 < 80

4.09

1.034–16.174

0.04

Histology

Squamous cell carcinoma

1.66

0.819–3.368

0.15

Operative procedure

RUL or RLL or LUL

2.65

1.083–6.495

0.03

  1. CEA carcinoembryonic antigen, PNI prognostic nutritional index, NLR neutrophil-to-lymphocyte ratio, FEV1% forced expiratory volume % in one second, RUL right upper lobectomy, RLL right lower lobectomy, LUL left upper lobectomy, RUL right upper lobectomy, RLL right lower lobectomy, LUL left upper lobectomy, BMI body mass index, VC vital capacity