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Table 3 Multivariate analysis of risk factors for postoperative morbidity and severe postoperative morbidity

From: Analysis of risk factors for postoperative complications in non-small cell lung cancer: comparison with the Japanese National Clinical Database risk calculator

Postoperative morbidity

Variables

 

Odds ratio

95% CI

P value

Comorbidity

COPD

1.35

0.645–2.859

0.41

 

Asthma

3.07

1.164–8.102

0.02

Smoking status

Brinkman index ≥ 600

1.38

0.901–2.129

0.13

CEA

 > 5

1.32

0.885–1.978

0.17

FEV1%

 < 70

1.49

0.984–2.257

0.05

NLR

 > 1.56

1.60

1.006–2.563

0.04

Histological type

Squamous cell carcinoma

1.20

0.729–1.977

0.47

Pulmonary lobe

RUL or RLL or LUL

2.01

1.224–3.314

 < 0.01

Operative procedure

Lobectomy or more

1.56

0.664–3.671

0.30

Postoperative severe morbidity

%VC

 < 80

6.10

1.888–19.712

 < 0.01

Pulmonary lobe

RUL or RLL or LUL

2.27

1.041–4.957

0.03

Operative procedure

Lobectomy or more

3.00

1.201–7.493

0.01

  1. COPD chronic obstructive pulmonary disease, CEA carcinoembryonic antigen, FEV1% forced expiratory volume % in one second, NLR neutrophil-to-lymphocyte ratio, BMI body mass index, VC vital capacity