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Table 4 Univariate and multivariate analysis for ΔAG predicting hospital mortality

From: Association between delta anion gap and hospital mortality for patients in cardiothoracic surgery recovery unit: a retrospective cohort study

Variables Odds ratios β 95% confidence interval p value
Univariate logistic regression
 ΔAG (≥ 7 vs < 7) 9.54 2.26 3.81–23.87 < 0.001
 ΔAG, continuous 1.24 0.21 1.16–1.32 < 0.001
 Gender (male vs female) 0.28 − 1.28 0.11–0.70 0.007
 Race (white vs non-white) 2.21 0.80 0.87–5.65 0.096
 Age 1.15 0.14 1.08–1.22 < 0.001
 Body mass index 0.99 0.00 0.93–1.08 0.986
 Serum Creatinine 1.34 0.29 1.12–1.61 0.002
 Urea nitrogen 1.04 0.04 1.03–1.06 < 0.001
 Lactate 1.87 0.62 1.55–2.24 < 0.001
 Base excess 0.75 − 0.28 0.70–0.82 < 0.001
 White blood cell 1.06 0.05 0.99–1.12 0.108
 AKF 8.87 2.18 3.55–22.21 < 0.001
 Acidosis 4.92 1.59 1.63–15.01 0.005
 Diabetes 1.24 0.21 0.49–3.15 0.655
 SAPSII 1.07 0.07 1.04–1.10 < 0.001
 SOFA 1.17 0.15 1.01–1.35 0.040
 SIRS 1.66 0.51 0.94–2.93 0.080
Multivariate logistic regression
 Model 1
  ΔAG, continuous 1.24 0.21 1.11–1.39 < 0.001
  Age 1.14 0.13 1.07–1.21 < 0.001
  Base excess 0.81 − 0.21 0.72–0.90 < 0.001
  AKF 14.87 2.69 2.81–77.55 0.001
  ΔAG × AKF 0.84 − 0.18 0.70–1.01 0.051
  Constant   − 15.69 − 20.98 to − 10.40 < 0.001
 Model 2
  ΔAG (≥ 7 vs < 7) 4.23 1.44 1.22–14.63 0.023
  Age 1.14 0.13 1.07–1.21 < 0.001
  Base excess 0.78 − 0.25 0.70–0.86 < 0.001
  AKF 7.81 2.06 1.59–38.47 0.011
  ΔAG × AKF 0.90 − 0.10 0.75–1.09 0.278
  1. The mean VIF of model 1 was 2.78
  2. AG anion gap, AKF acute kidney failure, SAPSII simplified acute physiology score II, SOFA sequential organ failure assessment, SIRS systemic inflammatory response syndrome