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Table 3 Univariate and multivariate analyses of prognostic factors with overall survival

From: Preoperative geriatric nutritional risk index is an independent prognostic factor for postoperative survival after gallbladder cancer radical surgery

Variables

Univariate analysis

Multivariate analysis

HR (95%CI)

P-value

HR (95% CI)

P-value

Age

1.026 (1.006–1.046)

0.009

1.030 (1.002–1.060)

0.038

Sex male

1.195 (0.779–1.832)

0.414

  

serum CA 19-9 (U/mL) > 37

2.304 (1.470–3.612)

 < 0.001

1.633(0.822–3.244)

0.161

Serum CEA (ng/mL) > 5

1.904 (1.192–3.041)

0.007

1.674(0.815–3.441)

0.161

Hemoglobin

1.192 (1.098–1.214)

0.038

1.023 (1.001–1.047)

0.047

NLR > 2.6

1.447 (0.963–2.174)

0.075

  

Gallstones

1.271 (0.821–1.970)

0.282

  

Tumor size > 3 cm

1.021 (0.639–1.633)

0.930

  

T III–IV

1.630 (1.253–2.121)

 < 0.001

0.338 (0.098–1.160)

0.085

Poor differentiation

2.323 (1.496–3.607)

 < 0.001

2.050 (1.070–4.300)

0.042

Lymph node metastases

1.567 (1.004–2.448)

0.048

0.806 (0.388–1.674)

0.563

TNM stage III + IV

3.688 (2.011–6.764)

 < 0.001

8.035 (1.708–37.812)

0.008

GNRI < 98

3.194 (2.098–4.861)

 < 0.001

2.207 (1.131–4.308)

0.020