Laparoscopic surgery does not reduce the need for red blood cell transfusion after resection for colorectal tumour: a propensity score match study on 728 patients

Table 4 Univariate and multivariable logistic regression analysing risk factors for postoperative RBC transfusion

	Univariate		Multivariable
	OR (95% CI)	P	OR (95% CI)	P
Age ≥ median	2.2 (1.4–3–3)	< 0.001
Male gender	1.1 (0.7–1.6)	0.76
Tumour location		0.05
Right colon	1
Left colon	0.5 (0.3–0.9)
Rectum	0.8 (0.5–1.3)
ASA physical status class ≥ 3	3.2 (1.7–6.2)	< 0.001
Presence of preoperative anaemia^a		< 0.001		< 0.001
No	1		1
Mild	3.3 (1.9–5.6)		4.4 (1.5–12.4)
Moderate	14.6 (8.3–25.8)		18.2 (5.9–56.3)
Preoperative RBC transfusions	7.4 (3.5–15.9)	< 0.001
Depth of tumour invasion ≥ pT3	1.5 (1.0–2.3)	0.04
Presence of nodal metastases (N+)	1.4 (0.9–2.2)	0.14
Open surgery	1.2 (0.8–1.9)	0.34
Postoperative complications	8.3 (5.1–13.6)	< 0.001	5.1 (2.2–11.5)	< 0.001
Severe postoperative complications^b	16.1 (8.5–30.5)	< 0.001	21.8 (7.5–63.4)	< 0.001
Surgical complications^b	10.3 (6.5–16.4)	< 0.001	8.9 (3.8–20.8)	< 0.001
Anastomotic leakages^b	19.7 (8.8–44.0)	< 0.001	38.1 (9.5–153.4)	< 0.001
Bleeding^b	21.8 (8.4–56.6)	< 0.001	14.6 (2.5–83.3)	0.003
Infective complications^b	4.1 (2.6–6.6)	< 0.001	7.2 (3.0–17.4)	< 0.001

OR odds ratio, 95% CI 95% confidence interval
^aPreoperative anaemia resulted a significant risk factor at multivariate analysis also when the type of postoperative complications were included in the model separately
^bType of postoperative complications were included in multivariate analysis separately

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