Table 3 Multivariate analysis of RFS in HCC patients with and without liver cirrhosis after hepatectomy

Gender, Female

0.9962 (0.9867–1.0059)

0.4422

–

–

–

–

–

–

Age

0.7328 (0.5493–0.9778)

0.0346*

0.9889 (0.9775–1.00)

0.059165

–

–

–

–

Smoking

1.0829 (0.8525–1.3754)

0.5141

–

–

–

–

–

–

Drinking

1.2703 (0.978–1.65)

0.073

–

–

–

–

–

–

AFP, > 400 μg/L

1.3121 (1.0661–1.6148)

0.0103*

1.097 (0.8434–1.427)

0.489999

1.147 (0.9112–1.444)

0.24273

1.1334 (0.855–1.502)

0.38402

ALBI, ≥ − 2.6

–

–

1.4341 (1.083–1.899)

0.011865*

1.312 (1.0511–1.638)

0.01638*

1.6894 (1.2586–2.268)

 < 0.001**

NLR, > 1.5

–

–

–

–

1.372 (1.0532–1.787)

0.01908*

–

–

Portal triad clamping time > 20 min

–

–

–

–

1.023 (0.7954–1.315)

0.86113

–

–

Intraoperative blood loss > 400 ml

1.1844 (0.8741–1.6048)

0.2749

–

–

1.284 (0.9336–1.767)

0.12405

0.8711 (0.5534–1.371)

0.55099

Intraoperative blood transfusion

0.7725 (0.5322–1.1214)

0.1747

1.3469 (0.9524–1.905)

0.092117

0.888 (0.6067–1.3)

0.54136

1.5102 (0.9274–2.459)

0.09752

Tumor diameter, > 5 cm

1.5473 (1.2527–1.9112)

< 0.001**

1.1343 (0.8637–1.49)

0.36473

1.631 (1.2927–2.059)

 < 0.001**

1.7445 (1.2685–2.399)

< 0.001**

Multiple tumors

–

–

–

–

–

–

1.009 (0.7229–1.408)

0.9579

Pathological grading III/IV

1.194 (0.9156–1.5571)

0.1905

0.9612 (0.686–1.347)

0.818020

1.175 (0.8665–1.592)

0.29973

1.2592 (0.8359–1.897)

0.27025

Satellite lesions, Yes

1.3558 (1.0718–1.715)

0.0111*

1.5619 (1.158–2.107)

0.003493**

1.742 (1.3648–2.223)

 < 0.001**

1.4556 (1.0462–2.025)

0.02588*

MVI

1.2347 (0.9805–1.5549)

0.073

1.8153 (1.3584–2.426)

< 0.001**

1.34 (1.045–1.717)

0.02105*

1.5081 (1.0753–2.115)

0.01729*

Macrovascular invasion

2.2488 (1.6697–3.0289)

< 0.001**

2.0051 (1.3567–2.963)

< 0.001**

1.65 (1.2055–2.26)

0.00177**

1.5668 (1.0402–2.36)

0.03167*

Lymphatic metastasis

2.0317 (1.1955–3.453)

0.008791**

–

3.202 (1.8585–5.516)

< 0.001**