Table 6 Univariate and multivariate logistic regression analysis of risk factors of pancreatic fistula following pancreaticoduodenectomy
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95%CI | P value | HR | 95%CI | P value | |
Age (≥ 65 or < 65) | 1.13 | 0.87–1.34 | 0.570 |  |  |  |
Gender (female/ male) | 0.83 | 0.42–1.32 | 0.981 |  |  |  |
BM (≥ 24 or < 24) | 3.54 | 1.94–5.37 | 0.019 | 2.86 | 1.85–4.26 | 0.016 |
Pancreatic duct diameter (mm, < 3 or ≥ 3) | 2.04 | 1.23–3.68 | 0.000 | 1.85 | 1.02–4.41 | 0.007 |
Duration of operation (h, ≥ 6.5 or < 6.5) | 1.27 | 0.87–1.54 | 0.405 |  |  |  |
Intraoperative blood loss (ml, ≥ 1000 or < 1000) | 1.03 | 0.15–1.47 | 0.656 |  |  |  |
Wrapping with omentum and improving pancreaticojejunostomy (no/ yes) | 4.34 | 2.26–6.73 | 0.035 | 4.02 | 1.85–5.81 | 0.010 |
Preoperative albumin (g/l, < 35 or ≥ 35) | 1.08 | 1.01–1.97 | 0.065 |  |  |  |
Bilirubin (umol/l, ≥ 34 or < 34) | 2.42 | 1.21–4.17 | 0.819 |  |  |  |
Postoperative pathology is benign and malignant (vicious/ good) | 1.34 | 0.47–2.16 | 0.919 |  |  |  |
Pancreatic texture (soft/firm) | 0.58 | 0.23–2.19 | 0.274 |  |  |  |