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Table 1 Demographic and clinical data of patients before and after propensity score matching

From: Short-term outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma in older patients: a propensity score matching analysis

 

Before matching

After matching

OLR (n = 145)

LLR (n = 133)

P

OLR (n = 75)

LLR (n = 75)

P

Age, years

76 (70–90)

75 (70–85)

0.393

75 (70–90)

75 (70–83)

0.649

Male sex

101 (69.7)

98 (73.7)

0.457

51 (68.0)

53 (70.7)

0.723

BMI, kg/m2

22.6 (15.3–32.0)

23.1 (16.4–34.5)

0.4

23.0 (15.3–29.9)

23.1 (16.6–34.5)

0.891

History of open abdominal surgery, n (%)

35 (24.1)

16 (12.0)

0.008

14 (18.7)

11 (14.7)

0.511

Preexisting medical condition

 Hypertension

78 (53.8)

84 (63.2)

0.114

46 (61.3)

43 (57.3)

0.618

 Diabetes mellitus

49 (33.8)

54 (40.6)

0.24

28 (37.3)

28 (37.3)

1.00

 Renal failure

12 (8.3)

9 (6.8)

0.634

5 (6.7)

7 (9.3)

0.547

 Ischemic heart disease

31 (21.4)

18 (13.5)

0.085

12 (16.0)

15 (20.0)

0.524

 COPD or pulmonary disease

10 (6.9)

9 (6.8)

0.966

5 (6.7)

6 (8.0)

0.754

Antiplatelet (aspirin) intake, n (%)

19 (13.1)

20 (15.4)

0.643

10 (13.3)

9 (12.0)

0.806

ASA classification

0.022

  

0.867

 I

0 (0)

0 (0)

 

0 (0)

0 (0)

 

 II

81 (55.7)

92 (69.2)

 

46 (61.3)

45 (60.0)

 

 III

64 (44.2)

41 (30.8)

 

29 (38.7)

30 (40.0)

 

Hepatitis status

0.07

  

0.569

 HBV positive

20 (13.8)

34 (25.5)

 

14 (18.7)

15 (20.0)

 

 HCV positive

77 (53.1)

56 (42.1)

 

42 (56.0)

34 (45.3)

 

 HBV HCV positive

2 (1.4)

3 (2.3)

 

1 (1.3)

1 (1.3)

 

 HBV HCV negative

46 (31.7)

40 (30.1)

 

18 (24.0)

25 (33.4)

 

Child–Pugh classification

0.662

  

0.699

 A

138 (95.2)

128 (96.2)

 

72 (96.0)

71 (94.7)

 

 B

7 (4.8)

5 (3.8)

 

3 (4.0)

4 (5.3)

 

AFP level (ng/mL)

10 (2.0–113,560)

6 (2.0–8900)

0.069

10 (2.0–5359)

8 (2–8900)

0.953

PIVKA-II level (mAU/mL)

103 (10–115,454)

48 (2.8–24,892)

0.041

51 (10–37,080)

56 (10–24,892)

0.451

PLT (× 104/μL)

14.4 (3.2–47.4)

15.6 (4–36)

0.056

14.7 (4.1–47.4)

14.6 (6.8–33.1)

0.638

ALB (g/L)

3.9 (2.8–4.8)

4.2 (2.8–5.1)

< 0.001

4.0 (2.8–4.8)

4.1 (2.8–5.0)

0.596

T-Bil (mg/L)

0.7 (0.2–2.2)

0.7 (0.2–1.9)

0.326

0.7 (0.3–2.2)

0.6 (0.2–1.9)

0.996

ALT (IU/L)

26 (6–175)

24 (2–227)

0.458

27 (9–175)

30 (2–101)

0.699

AST (IU/L)

32 (12–327)

30 (13–177)

0.149

33 (15–327)

30 (14–94)

0.777

Prothrombin time (%)

87 (60–100)

91 (68–100)

0.008

88 (66–100)

88 (68–100)

0.909

ICG-R15 (%)

13.9 (3.2–35.4)

13.0 (3.6–35.3)

0.071

13.0 (3.2–33.4)

14.4 (3.6–35.3)

0.578

Size of the largest tumor (mm)

27.0 (1.6–170)

23.0 (1.4–82)

0.012

21.0 (2.7–80)

24.0 (10–82)

0.239

Number of tumors

1 (1–4)

1 (1–3)

0.623

1 (1–4)

1 (1–3)

0.666

Surgical procedure, n (%)

0.319

  

0.726

 Right-sided hepatectomy (excision of any segment from segment 5–8)

105 (72.4)

89 (66.9)

 

52 (69.3)

50 (66.7)

 

 Left-sided hepatectomy (excision of any segment from segment 2–4)

40 (27.6)

44 (33.1)

 

23 (30.7)

25 (33.3)

 

Surgical procedure, n (%) (detailed surgical techniques)

< 0.001

  

0.961

 Limited liver resection or lateral sectionectomy

50 (34.5)

69 (51.9)

 

35 (46.7)

37 (49.3)

 

 Segmentectomy

29 (20.0)

34 (25.6)

 

18 (24.0)

17 (22.7)

 

 Sectionectomy

34 (23.4)

18 (13.5)

 

16 (21.3)

14 (18.7)

 

 Hemihepatectomy or more than three sectionectomy

32 (22.1)

12 (9.0)

 

6 (8.0)

7 (9.3)

 
  1. Data are presented as number (%) or median (range)
  2. AFP alpha-fetoprotein, ALB albumin, ALT alanine aminotransferase, ASA American Society of Anesthesiologists, ASA I normal healthy patient, ASA II patient with mild systemic disease, ASA III patient with severe systemic disease that is not incapacitating, AST aspartate aminotransferase, BMI body mass index, HBV hepatitis B virus, HCV hepatitis C virus, ICG-R15 indocyanine green retention rate at 15 min, LLR laparoscopic liver resection, N/A not applicable, OLR open liver resection, PIVKA-II protein induced by vitamin K absence, PLT platelets, T-Bil total bilirubin