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Table 1 Patients’ characteristics at surgery in the two groups

From: Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) vs CRS alone for treatment of endometrial cancer with peritoneal metastases: a multi-institutional study from PSOGI and BIG RENAPE groups

 

CRS only

n = 30

CRS + HIPEC

n = 30

Paired differences

p

Age (years)

63.9 (60.5;67.2)

60.9 (58.9;62.9)

− 2.5 (− 4.5;− 0.5)

0.004

Tumor histology

 

 Endometrioid adenocarcinoma

27 (90.0%)

27 (90.0%)

1

 Carcinosarcoma

1 (3.3%)

1 (3.3%)

  

 Other

2 (6.7%)

2 (6.7%)

  

Surgery

< 0.001

 Primary

25 (83.3%)

1 (3.3%)

− 80.0% (− 97.0%;−  63.0%)

 

 Recurrence

5 (16.7%)

29 (96.7%)

Months since diagnosis

2.1 (5.4;19.5)*

6.8 (5.1;9.2)*

3.9 (− 0.1;8.5)*

0.001

Systemic chemotherapy

 

 Neoadjuvant

3 (10.0%)

11 (44.7%)

30.7% (11.1%;50.4%)

0.011

 Adjuvant

27 (90.0%)

16 (59.4%)

 

PCI

10.0 (5.6;14.4)

9.9 (7.5;12.2]

− 0.1 (− 4.3;4.1)

0.702

CC score

 

 CC-0

21 (72.4%)

23 (79.3%)

6.9% (− 6.1%;29.9%)

0.763

 CC-1 or CC-2

8 (25.6%)

6 (20.7%)

 

Surgery duration (hours)

4.0 (3.3;4.6)

6.1 (5.3;6.9)

2.1 (1.0;3.1)

0.006

  1. Results presented as Mean and 95% confidence interval and frequency and percentage unless otherwise specified
  2. PCI: Peritoneal Cancer Index; Completeness of Cytoreduction Score (CC-S): CC-0 = no macroscopic residual cancer, CC-1 = residual nodules < 2.5 mm, CC-2 = residual nodule between 2.5 and 25 mm
  3. *Median and interquartile range
  4. Matching criteria
  5. 3 missing data
  6. 2 missing data